About   Help   FAQ
Trap1
Gene Detail
 Symbol
Name
ID
Trap1
TNF receptor-associated protein 1
MGI:1915265
Synonyms 2410002K23Rik, HSP75
Feature Type protein coding gene
Genetic Map
Chromosome 16
2.38 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr16:4039971-4077827 bp, - strand
From VEGA annotation of GRCm38

  37857 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9457  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: heat shock protein, HSP90/HTPG types
Gene Tree: Trap1

Human
homologs
Human Homolog TRAP1, TNF receptor-associated protein 1
NCBI Gene ID 10131
neXtProt AC  NX_Q12931
Human Synonyms  HSP75, HSP 75, HSP90L, TRAP-1
Human Chr (Location)  16p13.3; chr16:3658037-3717597 (-)  GRCh38
Alleles
and
phenotypes
All alleles(17) : Gene trapped(17)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process negative regulation of cellular respiration, negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress, ...
Component extracellular vesicular exosome, membrane, ...
Function ATP binding, nucleotide binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (3)    Tissues (2)    Images (1)
Theiler Stages: 23, 28
Assay TypeResults
RNA in situ 1
Northern blot 2
cDNA source data(135)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(135) cDNA(135)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000020070 (Evidence)
Ensembl Gene ModelENSMUSG00000005981 (Evidence)
Entrez Gene68015 (Evidence)
UniGene123366
DFCITC1572064
DoTSDT.101373505, DT.528975
NIA Mouse Gene IndexU036729
Consensus CDS ProjectCCDS27914.1
International Mouse Knockout Project StatusTrap1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020070 VEGA Gene Model | MGI Sequence Detail 37857 C57BL/6J ±  kb
transcript OTTMUST00000047741 VEGA | MGI Sequence Detail 2320 Not Applicable 
polypeptide OTTMUSP00000021685 VEGA | MGI Sequence Detail 706 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(4) UniProt(7)
Polymorphisms SNPs within 2kb(100 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001404 Heat shock protein Hsp90
InterPro IPR020575 Heat shock protein Hsp90, N-terminal
InterPro IPR003594 Histidine kinase-like ATPase, ATP-binding domain
InterPro IPR020568 Ribosomal protein S5 domain 2-type fold
Protein Ontology PR:000016610 heat shock protein 75 kDa, mitochondrial
References (Earliest) J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
(Latest) J:196161 Yoshida S, et al., Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis. Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):E1604-12
All references(46)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory