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Bambi
Gene Detail
 Symbol
Name
ID
Bambi
BMP and activin membrane-bound inhibitor
MGI:1915260
Synonyms 2610003H06Rik
Feature Type protein coding gene
Genetic Map
Chromosome 18
2.30 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:3507957-3516404 bp, + strand
From NCBI annotation of GRCm38

  8448 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8215  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: BMP and activin membrane-bound inhibitor
Gene Tree: Bambi

Human
homologs
Human Homolog BAMBI, BMP and activin membrane-bound inhibitor
NCBI Gene ID 25805
neXtProt AC  NX_Q13145
Human Synonyms  NMA
Human Chr (Location)  10p12.3-p11.2; chr10:28677495-28682939 (+)  GRCh38
Alleles
and
phenotypes
All alleles(5) : Targeted(5)
Incidental mutations (data from APF )
 
Female mice homozygous for a null allele weigh 9% to 10% less than wild-type female mice. Male mice are unaffected. Mice homozygous for one knock-out allele exhibit increased chemical, thermal, and mechanical nociception and decreased nerve injury-induced allodynia.
 
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process cell migration, negative regulation of transforming growth factor beta receptor signaling pathway, ...
Component cytoplasm, integral component of membrane, ...
Function frizzled binding
External Resources: FuncBase
Expression
Literature Summary: (16 records)
Data Summary: Results (609)    Tissues (217)    Images (84)
Theiler Stages: 2, 3, 4, 9, 11, 12, 15, 17, 19, 20, 21, 22, 23, 24, 28
Assay TypeResults
RNA in situ 563
RT-PCR 46
cDNA source data(31)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(38) cDNA(33) Primer pair(5)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000024232 (Evidence)
Entrez Gene68010 (Evidence)
UniGene284863
DFCITC1577865
DoTSDT.55100441
NIA Mouse Gene IndexU018352
Consensus CDS ProjectCCDS29034.1
International Mouse Knockout Project StatusBambi
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 68010 NCBI Gene Model | MGI Sequence Detail 8448 C57BL/6J ±  kb
transcript NM_026505 RefSeq | MGI Sequence Detail 5040 C57BL/6 
polypeptide Q9D0L6 UniProt | EBI | MGI Sequence Detail 260 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(26 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009345 BMP/activin membrane-bound inhibitor
Protein Ontology PR:000004636 BMP and activin membrane-bound inhibitor
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:208107 Lantero A, et al., TGF-beta and Opioid Receptor Signaling Crosstalk Results in Improvement of Endogenous and Exogenous Opioid Analgesia under Pathological Pain Conditions. J Neurosci. 2014 Apr 9;34(15):5385-95
All references(48)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory