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Nacc2 Gene Detail
Summary
  • Symbol
    Nacc2
  • Name
    nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
  • Synonyms
    0610020I02Rik, Btbd14a, C030048H19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915241
    NCBI Gene: 67991
  • Alliance
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:26055535-26122811 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 18.29 cM, cytoband A3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    324 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915241
protein coding gene Chr2:26055535-26123220 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025477
protein coding gene Chr2:23997317-24067237 (-)
A/J MGP_AJ_G0025454
protein coding gene Chr2:23069072-23137218 (-)
AKR/J MGP_AKRJ_G0025424
protein coding gene Chr2:23820606-23889611 (-)
BALB/cJ MGP_BALBcJ_G0025450
protein coding gene Chr2:23179079-23249008 (-)
C3H/HeJ MGP_C3HHeJ_G0025211
protein coding gene Chr2:23764997-23853027 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025894
protein coding gene Chr2:24765017-24842391 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023305
protein coding gene Chr2:21950115-22021440 (-)
CAST/EiJ MGP_CASTEiJ_G0024674
protein coding gene Chr2:23642003-23722618 (-)
CBA/J MGP_CBAJ_G0025189
protein coding gene Chr2:25604695-25680371 (-)
DBA/2J MGP_DBA2J_G0025322
protein coding gene Chr2:22894071-22963444 (-)
FVB/NJ MGP_FVBNJ_G0025284
protein coding gene Chr2:22645578-22713640 (-)
LP/J MGP_LPJ_G0025408
protein coding gene Chr2:23931106-24004188 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025315
protein coding gene Chr2:25772567-25843036 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025953
protein coding gene Chr2:23783826-23855698 (-)
PWK/PhJ MGP_PWKPhJ_G0024422
protein coding gene Chr2:22696303-22765953 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024222
protein coding gene Chr2:23905133-23978118 (-)
WSB/EiJ MGP_WSBEiJ_G0024743
protein coding gene Chr2:23880292-23953994 (-)



Homology
more
  • Human Ortholog
    NACC2, NACC family member 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NACC2, NACC family member 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BEND9, BTBD14, BTBD14A, BTBD31, NAC-2, RBB
  • Links
    NCBI Gene ID: 138151
    neXtProt AC: NX_Q96BF6
    UniProt: Q96BF6

  • Chr Location
    9q34.3; chr9:136006537-136095285 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 75239
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: NACC2
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67991 NCBI Gene Model | MGI Sequence Detail 67277 C57BL/6J ±  kb
    transcript NM_001037098 RefSeq | MGI Sequence Detail 6893 C57BL/6  
    polypeptide Q9DCM7 UniProt | EBI | MGI Sequence Detail 586 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 68
      cDNA 68

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1915386, MGI:2138951
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    03/13/2019
    MGI 6.13
    The Jackson Laboratory