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Hormad1
Gene Detail
Symbol

Name
ID
Hormad1
HORMA domain containing 1
MGI:1915231
Synonyms
4921522K05Rik, Nohma
Feature Type
protein coding gene
Genetic Map
Chromosome 3
40.74 cM, cytoband F2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:95559677-95587671 bp, + strand
From VEGA annotation of GRCm38

  27995 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:69415  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: HORMAD1
Protein SuperFamily: conserved protein with HORMA-domain
Gene Tree: Hormad1

Human
homologs
HORMAD1, HORMA domain containing 1
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 84072
neXtProt AC: NX_Q86X24

Human Synonyms: CT46, NOHMA

Human Chr (Location): 1q21.3; chr1:150698059-150720909 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(14) : Gene trapped(7) Targeted(7)
Incidental mutations (data from Mutagenetix , APF )
 
Homozgous mice are infertile because of meiosis arrest associated with impaired synaptonemal-complex formation.
 
Interactions
Hormad1 interacts with 78 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process blastocyst development, cell differentiation, ...
Component chromosome, condensed nuclear chromosome, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (6 records)
Data Summary: Results (39)    Tissues (23)    Images (14)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 14
Northern blot 16
RT-PCR 9
cDNA source data(8)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase hormad1 ; ZFIN hormad1    NEW 
Molecular
reagents
All nucleic(12) cDNA(9) Primer pair(2) Other(1)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000022048 (Evidence)
Ensembl Gene Model ENSMUSG00000028109 (Evidence)
Entrez Gene 67981 (Evidence)
UniGene 179050
DFCI TC1587756, TC1594464, TC1646467
DoTS DT.50316319, DT.111062419, DT.101368941
NIA Mouse Gene Index U055443, U003572
Consensus CDS Project CCDS38547.1, CCDS71292.1
International Mouse Phenotyping Consortium Status Hormad1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022048 VEGA Gene Model | MGI Sequence Detail 27995 C57BL/6J ±  kb
transcript OTTMUST00000052344 VEGA | MGI Sequence Detail 1385 Not Applicable 
polypeptide OTTMUSP00000024807 VEGA | MGI Sequence Detail 392 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(12) UniProt(1)
Polymorphisms
SNPs within 2kb(82 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003511 DNA-binding HORMA
Protein Ontology PR:000030953 HORMA domain-containing protein 1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:211664 Winters T, et al., Meiotic cohesin STAG3 is required for chromosome axis formation and sister chromatid cohesion. EMBO J. 2014 Jun 2;33(11):1256-70
All references(41)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory