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Pold3
Gene Detail
Symbol

Name
ID
Pold3
polymerase (DNA-directed), delta 3, accessory subunit
MGI:1915217
Synonyms
2410142G14Rik, C85233, GC12, P66, P68
Feature Type
protein coding gene
Genetic Map
Chromosome 7
54.32 cM, cytoband F1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:100082111-100121565 bp, - strand
From VEGA annotation of GRCm38

  39455 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:38202  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Pold3

Human
homologs
Human Homolog POLD3, polymerase (DNA-directed), delta 3, accessory subunit
NCBI Gene ID 10714
neXtProt AC  NX_Q15054
Human Synonyms  P66, P68, PPP1R128
Human Chr (Location)  11q14; chr11:74592530-74669341 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(19) : Gene trapped(17) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pold3 interacts with 258 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process DNA-dependent DNA replication, DNA replication, ...
Component mitochondrion, nucleoplasm, ...
Function DNA-directed DNA polymerase activity, nucleotidyltransferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (137)    Tissues (123)    Images (27)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 137
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000025292 (Evidence)
Ensembl Gene ModelENSMUSG00000030726 (Evidence)
Entrez Gene67967 (Evidence)
DFCITC1726061, TC1574800
DoTSDT.97332194, DT.87072566, DT.87025150
NIA Mouse Gene IndexU028908
Consensus CDS ProjectCCDS21493.1
International Mouse Knockout Project StatusPold3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025292 VEGA Gene Model | MGI Sequence Detail 39455 C57BL/6J ±  kb
transcript OTTMUST00000062244 VEGA | MGI Sequence Detail 3069 Not Applicable 
polypeptide OTTMUSP00000030660 VEGA | MGI Sequence Detail 461 Not Applicable 

For the selected sequences
All sequences(60) RefSeq(6) UniProt(9)
Polymorphisms
SNPs within 2kb(340 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR019038 DNA polymerase subunit Cdc27
Protein Ontology PR:000012965 DNA polymerase delta subunit 3
References
(Earliest) J:113822 Zeng XR, et al., DNA polymerase delta is involved in the cellular response to UV damage in human cells. J Biol Chem. 1994 May 13;269(19):13748-51
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(44)
Other
accession IDs
MGI:2142354

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory