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Puf60 Gene Detail
Summary
  • Symbol
    Puf60
  • Name
    poly-U binding splicing factor 60
  • Synonyms
    2410104I19Rik, 2810454F19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915209
    NCBI Gene: 67959
  • Gene Overview
    MyGene.info: PUF60
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:76070182-76080924 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 35.32 cM, cytoband E1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915209
protein coding gene Chr15:76070182-76080949 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021974
protein coding gene Chr15:76122246-76133010 (-)
A/J MGP_AJ_G0021932
protein coding gene Chr15:73354186-73364948 (-)
AKR/J MGP_AKRJ_G0021915
protein coding gene Chr15:75340810-75351570 (-)
BALB/cJ MGP_BALBcJ_G0021941
protein coding gene Chr15:73372902-73383664 (-)
C3H/HeJ MGP_C3HHeJ_G0021713
protein coding gene Chr15:75395677-75406439 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022381
protein coding gene Chr15:78962405-78973167 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019910
protein coding gene Chr15:70020726-70031743 (-)
CAST/EiJ MGP_CASTEiJ_G0021232
protein coding gene Chr15:76181275-76192459 (-)
CBA/J MGP_CBAJ_G0021680
protein coding gene Chr15:81477680-81488442 (-)
DBA/2J MGP_DBA2J_G0021805
protein coding gene Chr15:72883517-72894279 (-)
FVB/NJ MGP_FVBNJ_G0021786
protein coding gene Chr15:71935734-71946496 (-)
LP/J MGP_LPJ_G0021876
protein coding gene Chr15:76215003-76225764 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021810
protein coding gene Chr15:86779446-86790205 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022401
protein coding gene Chr15:75589328-75600090 (-)
PWK/PhJ MGP_PWKPhJ_G0020973
protein coding gene Chr15:73031142-73042314 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020812
protein coding gene Chr15:75309453-75320500 (-)
WSB/EiJ MGP_WSBEiJ_G0021284
protein coding gene Chr15:75673304-75684063 (-)



Homology
more
  • Human Ortholog
    PUF60, poly(U) binding splicing factor 60
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PUF60, poly(U) binding splicing factor 60
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FIR, RoBPI, SIAHBP1, VRJS
  • Links
    NCBI Gene ID: 22827
    neXtProt AC: NX_Q9UHX1
    UniProt: Q9UHX1

  • Chr Location
    8q24.3; chr8:143816344-143829386 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 8614
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: PUF60
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    27 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000002524 Ensembl Gene Model | MGI Sequence Detail 10743 C57BL/6J ±  kb
transcript ENSMUST00000100527 Ensembl | MGI Sequence Detail 1881 Not Applicable  
polypeptide ENSMUSP00000098096 Ensembl | MGI Sequence Detail 564 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 6
Other
Accession IDs
less
MGI:1920052
References
more
  • Summaries
    All 52
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 3
    Phenotypes 27
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory