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March5
Gene Detail
 Symbol
Name
ID
March5
membrane-associated ring finger (C3HC4) 5
MGI:1915207
Synonyms 1810015H18Rik, 2310008I22Rik, 2700055A20Rik, 5730499H23Rik, E130202O05Rik, MARCH-V, MITOL, Rnf153
Feature Type protein coding gene
Genetic Map
Chromosome 19
32.20 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr19:37207543-37222139 bp, + strand
From VEGA annotation of GRCm38

  14597 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9862  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: March5

Human
homologs
Human Homolog MARCH5, membrane-associated ring finger (C3HC4) 5
NCBI Gene ID 54708
neXtProt AC  NX_Q9NX47
Human Synonyms  MARCH-V, MITOL, RNF153
Human Chr (Location)  10q23.32-q23.33; chr10:92291163-92353964 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(10) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
March5 interacts with 216 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (27 annotations)
Process negative regulation of cell aging, positive regulation of mitochondrial fission, ...
Component endoplasmic reticulum, endoplasmic reticulum membrane, ...
Function coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity, ...
External Resources: FuncBase
Expression
cDNA source data(122)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(122) cDNA(122)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000016844 (Evidence)
Ensembl Gene ModelENSMUSG00000023307 (Evidence)
Entrez Gene69104 (Evidence)
UniGene175989
DFCITC1574804, TC1587667, TC1620253, TC1639247, TC1674203
DoTSDT.495628, DT.87072198, DT.91439532, DT.97407246
NIA Mouse Gene IndexU019406, U041109, U073629, U266378
EC6.3.2.-
Consensus CDS ProjectCCDS29776.1, CCDS50427.1
International Mouse Knockout Project StatusMarch5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016844 VEGA Gene Model | MGI Sequence Detail 14597 C57BL/6J ±  kb
transcript OTTMUST00000040925 VEGA | MGI Sequence Detail 1797 Not Applicable 
polypeptide OTTMUSP00000018307 VEGA | MGI Sequence Detail 278 Not Applicable 

For the selected sequences
All sequences(62) RefSeq(8) UniProt(3)
Polymorphisms SNPs within 2kb(27 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011016 Zinc finger, RING-CH-type
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
Protein Ontology PR:000010179 E3 ubiquitin-protein ligase MARCH5
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:199253 Sugiura A, et al., MITOL Regulates Endoplasmic Reticulum-Mitochondria Contacts via Mitofusin2. Mol Cell. 2013 Jul 11;51(1):20-34
All references(35)
Other
accession IDs
MGI:1916354, MGI:1917342, MGI:1917884, MGI:1925979

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory