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Tomm20 Gene Detail
Summary
  • Symbol
    Tomm20
  • Name
    translocase of outer mitochondrial membrane 20
  • Synonyms
    1810060K07Rik, MGC:6333, mKIAA0016, TOM20
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915202
    NCBI Gene: 67952
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:127657417-127672594 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 74.64 cM, cytoband E2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    390 from dbSNP Build 142
  • Strain Annotations
    20
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915202
 protein coding gene Chr8:127657414-127672671 (-)
129S1/SvImJ ENSMUSG00200005757
 protein coding gene Chr13:2048513-2049567 (+)
129S1/SvImJ ENSMUSG00200004543
 protein coding gene Chr8:121915916-121931089 (-)
A/J ENSMUSG00195011771
 protein coding gene Chr13:1456811-1457865 (+)
A/J ENSMUSG00195003598
 protein coding gene Chr8:122188386-122203570 (-)
AKR/J ENSMUSG00220001676
 protein coding gene Chr8:122376264-122391445 (-)
BALB/cJ ENSMUSG00180009017
 protein coding gene Chr13:1868966-1870021 (+)
BALB/cJ ENSMUSG00180000913
 protein coding gene Chr8:122233120-122248303 (-)
C3H/HeJ ENSMUSG00175005133
 protein coding gene Chr8:122309801-122324982 (-)
C57BL/6NJ ENSMUSG00215000688
 protein coding gene Chr8:121890561-121905738 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031731
 protein coding gene Chr8:118045579-118060053 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210013940
 protein coding gene Chr8:122222306-122237481 (-)
DBA/2J ENSMUSG00185035295
 protein coding gene Chr8:128541330-128556506 (-)
FVB/NJ ENSMUSG00205031076
 protein coding gene Chr8:121189810-121204988 (-)
FVB/NJ ENSMUSG00205021243
 protein coding gene Chr13:1873460-1874515 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230006833
 protein coding gene Chr8:132098405-132113577 (-)
NOD/ShiLtJ ENSMUSG00190006756
 protein coding gene Chr8:122333243-122348419 (-)
NZO/HlLtJ ENSMUSG00225019082
 protein coding gene Chr8:135453737-135468915 (-)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010001646
 protein coding gene Chr8:124219711-124234418 (-)
WSB/EiJ ENSIUOG00005002995
 protein coding gene Chr8:122999672-123014847 (-)



Homology
more
  • Human Ortholog
    TOMM20, translocase of outer mitochondrial membrane 20
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TOMM20, translocase of outer mitochondrial membrane 20
  • Synonyms
    MAS20, MOM19, TOM20
  • Links
    NCBI Gene ID: 9804
    UniProt: Q15388

  • Chr Location
    1q42.3; chr1:235109341-235128846 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    1 images
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele show complete embryonic lethality prior to organogenesis. In vitro, blastocysts do not hatch from the zona pellucida or form outgrowths.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    39
  • GO References
    22
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    696
  • Tissues
    38
  • cDNA Data
    13
  • Literature Summary
    48
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000093904 Ensembl Gene Model | MGI Sequence Detail 15178 C57BL/6J ±  kb
transcript ENSMUST00000179857 Ensembl | MGI Sequence Detail 4902 Not Applicable  
polypeptide ENSMUSP00000136493 Ensembl | MGI Sequence Detail 145 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000016532 mitochondrial import receptor subunit TOM20
    (term hierarchy)
  • InterPro Domains
    IPR023392 Mitochondrial outer membrane translocase complex, Tom20 domain superfamily
    IPR002056 Protein import receptor MAS20
    IPR022422 Protein import receptor MAS20, metazoan
Molecular
Reagents
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  • All nucleic 13
    cDNA 13
    Antibodies 7

    Microarray probesets 5
Other
Accession IDs
less
MGI:3034507
References
more
  • Summaries
    All 115
    Developmental Gene Expression 48
    Gene Ontology 22
    Phenotypes 14
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:391312 Rhon-Calderon EA, et al., Mouse offspring conceived by in vitro fertilization exhibit accelerated reproductive aging through premature ovarian insufficiency. J Clin Invest. 2026 Aug 17;136(16)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory