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Nifk Gene Detail
Summary
  • Symbol
    Nifk
  • Name
    nucleolar protein interacting with the FHA domain of MKI67
  • Synonyms
    C130020J04Rik, Mki67ip
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915199
    NCBI Gene: 67949
  • Gene Overview
    MyGene.info: NIFK
Location & Maps
more
  • Sequence Map
    Chr1:118321839-118333822 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11984 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 52.14 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    NIFK, nucleolar protein interacting with the FHA domain of MKI67
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NIFK, nucleolar protein interacting with the FHA domain of MKI67
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MKI67IP, Nopp34
  • Links
    NCBI Gene ID: 84365
    neXtProt AC: NX_Q9BYG3

  • Chr Location
    2q14.3; chr2:121726945-121736927 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 49862
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: NIFK
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    2
  • Gene trapped
    4
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    3 involving Nifk
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034779 VEGA Gene Model | MGI Sequence Detail 11984 C57BL/6J ±  kb
transcript OTTMUST00000088395 VEGA | MGI Sequence Detail 1889 Not Applicable  
polypeptide OTTMUSP00000048165 VEGA | MGI Sequence Detail 317 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    80 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000029630 MKI67 FHA domain-interacting nucleolar phosphoprotein
  • InterPro Domains
    IPR021043 MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding
    IPR012677 Nucleotide-binding alpha-beta plait domain
    IPR000504 RNA recognition motif domain
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 4
Other
Accession IDs
less
MGI:2138364
References
more
  • Summaries
    All 25
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory