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Prorsd1 Gene Detail
Summary
  • Symbol
    Prorsd1
  • Name
    prolyl-tRNA synthetase domain containing 1
  • Synonyms
    2010316F05Rik, Ncrna00117, Prdxdd1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915189
    NCBI Gene: 67939
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:29461757-29465033 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 16.75 cM, cytoband A4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    35 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915189
protein coding gene Chr11:29461757-29465033 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018107
protein coding gene Chr11:27516485-27519761 (-)
A/J MGP_AJ_G0018079
protein coding gene Chr11:26505078-26508347 (-)
AKR/J MGP_AKRJ_G0018044
protein coding gene Chr11:27367915-27371184 (-)
BALB/cJ MGP_BALBcJ_G0018047
protein coding gene Chr11:26709220-26712496 (-)
C3H/HeJ MGP_C3HHeJ_G0017861
protein coding gene Chr11:27278030-27281299 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018500
protein coding gene Chr11:28462606-28465882 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016157
protein coding gene Chr11:25148859-25152190 (-)
CAST/EiJ MGP_CASTEiJ_G0017423
protein coding gene Chr11:27336376-27341046 (-)
CBA/J MGP_CBAJ_G0017835
protein coding gene Chr11:29805981-29809265 (-)
DBA/2J MGP_DBA2J_G0017945
protein coding gene Chr11:26364783-26368052 (-)
FVB/NJ MGP_FVBNJ_G0017937
protein coding gene Chr11:26163975-26167251 (-)
LP/J MGP_LPJ_G0018017
protein coding gene Chr11:27776247-27779523 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017963
protein coding gene Chr11:30895156-30898425 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018540
protein coding gene Chr11:27464430-27467714 (-)
PWK/PhJ MGP_PWKPhJ_G0017205
protein coding gene Chr11:26454235-26459946 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017000
protein coding gene Chr11:27154067-27157327 (-)
WSB/EiJ MGP_WSBEiJ_G0017476
protein coding gene Chr11:27168303-27171579 (-)



Homology
more
  • Human Ortholog
    PRORSD1P, prolyl-tRNA synthetase associated domain containing 1, pseudogene
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRORSD1P, prolyl-tRNA synthetase associated domain containing 1, pseudogene
  • Synonyms
    NCRNA00117, Prdxdd1, PRDXDD1P, ProX, ProXp-ala, Ybakd1
  • Links
    NCBI Gene ID: 344405
    UniProt: A6NEY8

  • Chr Location
    2p16.1; chr2:55282319-55284522 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    24
  • Chemically induced (other)
    1
  • Gene trapped
    20
  • Targeted
    3
  • Genomic Mutations
    1 involving Prorsd1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 67939 NCBI Gene Model | MGI Sequence Detail 3277 C57BL/6J ±  kb
transcript NM_001163454 RefSeq | MGI Sequence Detail 2128 C57BL/6  
polypeptide Q9D820 UniProt | EBI | MGI Sequence Detail 169 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000033158 prolyl-tRNA synthetase associated domain-containing protein 1
  • InterPro Domains
    IPR040285 Prolyl-tRNA editing protein ProX/PRXD1
    IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain
    IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily
Molecular
Reagents
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  • All nucleic 25
    cDNA 23
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:286215 De Angelis MT, et al., Novel pancreas organogenesis markers refine the pancreatic differentiation roadmap of embryonic stem cells. Stem Cell Rev Rep. 2014 Apr;10(2):269-79

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory