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Ube2f Gene Detail
Summary
  • Symbol
    Ube2f
  • Name
    ubiquitin-conjugating enzyme E2F (putative)
  • Synonyms
    2510010F15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915171
    NCBI Gene: 67921
Location & Maps
more
  • Sequence Map
    Chr1:91250304-91290337 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      40034 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 46.08 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    UBE2F, ubiquitin conjugating enzyme E2 F (putative)
  • Vertebrate Orthologs
    10
  • Human Ortholog
    UBE2F, ubiquitin conjugating enzyme E2 F (putative)
    Orthology source: HGNC, HomoloGene
  • Synonyms
    NCE2
  • Links
    NCBI Gene ID: 140739
    neXtProt AC: NX_Q969M7

  • Chr Location
    2q37.3; chr2:237966945-238042782 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    1
  • Gene trapped
    7
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Ube2f
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000048490 VEGA Gene Model | MGI Sequence Detail 40034 C57BL/6J ±  kb
transcript OTTMUST00000124276 VEGA | MGI Sequence Detail 1154 Not Applicable  
polypeptide OTTMUSP00000067653 VEGA | MGI Sequence Detail 185 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    288 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000031611 NEDD8-conjugating enzyme UBE2F
  • EC
  • InterPro Domains
    IPR023313 Ubiquitin-conjugating enzyme, active site
    IPR000608 Ubiquitin-conjugating enzyme E2
    IPR016135 Ubiquitin-conjugating enzyme/RWD-like
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 6
Other
Accession IDs
less
MGI:2138354
References
more
  • Summaries
    All 27
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:149160 Huang DT, et al., E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification. Mol Cell. 2009 Feb 27;33(4):483-95

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory