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Zcchc3 Gene Detail
Summary
  • Symbol
    Zcchc3
  • Name
    zinc finger, CCHC domain containing 3
  • Synonyms
    2810406K24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915167
    NCBI Gene: 67917
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:152411955-152415027 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 74.98 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    35 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915167
protein coding gene Chr2:152411955-152415044 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026659
protein coding gene Chr2:156950011-156955345 (-)
A/J MGP_AJ_G0026625
protein coding gene Chr2:150698092-150701100 (-)
AKR/J MGP_AKRJ_G0026595
protein coding gene Chr2:155096424-155099495 (-)
BALB/cJ MGP_BALBcJ_G0026634
protein coding gene Chr2:151007673-151010746 (-)
C3H/HeJ MGP_C3HHeJ_G0026377
protein coding gene Chr2:155480218-155483287 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027083
protein coding gene Chr2:161534722-161539597 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024454
protein coding gene Chr2:144287115-144290168 (-)
CAST/EiJ MGP_CASTEiJ_G0025838
protein coding gene Chr2:155713660-155716720 (-)
CBA/J MGP_CBAJ_G0026355
protein coding gene Chr2:167445988-167449051 (-)
DBA/2J MGP_DBA2J_G0026491
protein coding gene Chr2:149914141-149917108 (-)
FVB/NJ MGP_FVBNJ_G0026457
protein coding gene Chr2:148355551-148360551 (-)
LP/J MGP_LPJ_G0026595
protein coding gene Chr2:157111500-157114565 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026478
protein coding gene Chr2:171553329-171557928 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027139
protein coding gene Chr2:154981926-154985222 (-)
PWK/PhJ MGP_PWKPhJ_G0025572
protein coding gene Chr2:149430692-149433750 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025375
protein coding gene Chr2:153804835-153808461 (-)
WSB/EiJ MGP_WSBEiJ_G0025908
protein coding gene Chr2:155903267-155906332 (-)



Homology
more
  • Human Ortholog
    ZCCHC3, zinc finger CCHC-type containing 3
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ZCCHC3, zinc finger CCHC-type containing 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C20orf99
  • Links
    NCBI Gene ID: 85364
    neXtProt AC: NX_Q9NUD5
    UniProt: Q9NUD5

  • Chr Location
    20p13; chr20:297563-300321 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Zcchc3
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000074682 Ensembl Gene Model | MGI Sequence Detail 3073 C57BL/6J ±  kb
transcript ENSMUST00000099207 Ensembl | MGI Sequence Detail 3073 Not Applicable  
polypeptide ENSMUSP00000096813 Ensembl | MGI Sequence Detail 400 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 62
    cDNA 62

    Microarray probesets 5
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:271802 Lian H, et al., ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response. Nat Commun. 2018 Aug 22;9(1):3349

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/14/2019
MGI 6.14
The Jackson Laboratory