About   Help   FAQ
Rgs19
Gene Detail
 Symbol
Name
ID
Rgs19
regulator of G-protein signaling 19
MGI:1915153
Synonyms 2610042F04Rik
Feature Type protein coding gene
Genetic Map
Chromosome 2
103.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:181688419-181693977 bp, - strand
From VEGA annotation of GRCm38

  5559 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23320  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: regulator of G protein signaling, RGS4 type
Gene Tree: Rgs19

Human
homologs
Human Homolog RGS19, regulator of G-protein signaling 19
NCBI Gene ID 10287
neXtProt AC  NX_P49795
Human Synonyms  GAIP, RGSGAIP
Human Chr (Location)  20q13.33; chr20:64073181-64080003 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(5) Targeted(1)
Incidental mutations (data from APF )
Interactions
Rgs19 interacts with 107 markers (Mir1a-1, Mir1a-2, Mir9-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process negative regulation of signal transduction, positive regulation of GTPase activity, ...
Component brush border, clathrin-coated vesicle, ...
Function G-protein alpha-subunit binding, GTPase activator activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (12)    Tissues (7)    Images (14)
Theiler Stages: 20, 21, 22, 23
Assay TypeResults
RNA in situ 12
cDNA source data(59)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(61) cDNA(59) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000016814 (Evidence)
Ensembl Gene ModelENSMUSG00000002458 (Evidence)
Entrez Gene56470 (Evidence)
UniGene274366
DFCITC1575828, TC1588735, TC1613027, TC1681513, TC1688443
DoTSDT.101377360, DT.110708228, DT.110708236, DT.492580, DT.91343795, DT.99857363, DT.99857365, DT.99857368
NIA Mouse Gene IndexU023795
Consensus CDS ProjectCCDS17220.1, CCDS71222.1, CCDS71223.1
International Mouse Knockout Project StatusRgs19
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016814 VEGA Gene Model | MGI Sequence Detail 5559 C57BL/6J ±  kb
transcript OTTMUST00000040846 VEGA | MGI Sequence Detail 1427 Not Applicable 
polypeptide OTTMUSP00000018271 VEGA | MGI Sequence Detail 243 Not Applicable 

For the selected sequences
All sequences(108) RefSeq(22) UniProt(9)
Polymorphisms All PCR and RFLP(3) : PCR(2) RFLP(1) SNPs within 2kb(50 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR024066 Regulator of G-protein signaling, domain 1
InterPro IPR000342 Regulator of G protein signalling
InterPro IPR016137 Regulator of G protein signalling superfamily
Protein Ontology PR:000013953 regulator of G-protein signaling 19
References (Earliest) J:64809 De Vries L, et al., GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIP. Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12340-5
(Latest) J:188786 Sohn WJ, et al., Rgs19 regulates mouse palatal fusion by modulating cell proliferation and apoptosis in the MEE. Mech Dev. 2012 Sep;129(9-12):244-54
All references(42)
Other
accession IDs
MGI:2138902, MGI:2139380

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/19/2014
MGI 5.19
The Jackson Laboratory