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Rgs19 Gene Detail
Summary
  • Symbol
    Rgs19
  • Name
    regulator of G-protein signaling 19
  • Synonyms
    2610042F04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915153
    NCBI Gene: 56470
  • Alliance
    genome feature page
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:181330212-181335770 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 103.72 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    138 from dbSNP Build 142
  • Strain Annotations
    19
  • PCR
    2
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915153
 protein coding gene Chr2:181330212-181336330 (-)
129S1/SvImJ ENSMUSG00200002018
 protein coding gene Chr2:177353013-177358571 (-)
A/J ENSMUSG00195001026
 protein coding gene Chr2:177583806-177589304 (-)
AKR/J ENSMUSG00220000076
 protein coding gene Chr2:175262468-175267966 (-)
BALB/cJ ENSMUSG00180000683
 protein coding gene Chr2:175393975-175399533 (-)
C3H/HeJ ENSMUSG00175004281
 protein coding gene Chr2:176544354-176549852 (-)
C57BL/6NJ ENSMUSG00215002529
 protein coding gene Chr2:175492335-175497893 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024818
 protein coding gene Chr2:171224495-171230065 (-)
CAST/EiJ ENSTCUG00005000513
 protein coding gene Chr2:174843181-174848813 (-)
CBA/J ENSMUSG00210001398
 protein coding gene Chr2:175870803-175876361 (-)
DBA/2J ENSMUSG00185020628
 protein coding gene Chr2:177103814-177109312 (-)
FVB/NJ ENSMUSG00205002028
 protein coding gene Chr2:175922411-175927969 (-)
JF1/MsJ ENSUMUG00000012308
 protein coding gene Chr2:178297447-178303082 (-)
LP/J ENSMUSG00230023643
 protein coding gene Chr2:179003909-179009467 (-)
NOD/ShiLtJ ENSMUSG00190015153
 protein coding gene Chr2:175412433-175417991 (-)
NZO/HlLtJ ENSMUSG00225005953
 protein coding gene Chr2:187085981-187091539 (-)
PWK/PhJ ENSLUMG00010000115
 protein coding gene Chr2:175717200-175722831 (-)
SPRET/EiJ ENSMSPG00010003719
 protein coding gene Chr2:178188236-178193793 (-)
WSB/EiJ ENSIUOG00005000173
 protein coding gene Chr2:175437934-175443432 (-)



Homology
more
  • Human Ortholog
    RGS19, regulator of G protein signaling 19
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RGS19, regulator of G protein signaling 19
  • Synonyms
    GAIP, RGSGAIP
  • Links
    NCBI Gene ID: 10287
    UniProt: P49795

  • Chr Location
    20q13.33; chr20:64073181-64079988 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    615
  • Tissues
    11
  • cDNA Data
    61
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000002458 Ensembl Gene Model | MGI Sequence Detail 5559 C57BL/6J ±  kb
transcript ENSMUST00000108778 Ensembl | MGI Sequence Detail 1427 Not Applicable  
polypeptide ENSMUSP00000104408 Ensembl | MGI Sequence Detail 243 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 63
    cDNA 61
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:2138902, MGI:2139380
References
more
  • Summaries
    All 49
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 11
  • Earliest
    J:64809 De Vries L, et al., GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIP. Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12340-5
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory