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Ccdc80
Gene Detail
Symbol

Name
ID
Ccdc80
coiled-coil domain containing 80
MGI:1915146
Synonyms
2610001E17Rik, DRO1, Ssg1, Urb
Feature Type
protein coding gene
Genetic Map
Chromosome 16
29.39 cM, cytoband B5
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr16:45093402-45127665 bp, + strand
From VEGA annotation of GRCm38

  34264 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12206  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Ccdc80

Human
homologs
Human Homolog CCDC80, coiled-coil domain containing 80
NCBI Gene ID 151887
neXtProt AC  NX_Q76M96
Human Synonyms  DRO1, okuribin, SSG1, URB
Human Chr (Location)  3q13.2; chr3:112604386-112641143 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit increased body fat, increased circulating leptin, glucose and free fatty acid levels, impaired glucose tolerance, increased insulin secretion, and islet hyperplasia when fed a high fat diet.
 
Interactions
Ccdc80 interacts with 149 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (7)    Tissues (7)    Images (4)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 6
RNA in situ 1
cDNA source data(104)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(106) cDNA(104) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000025346 (Evidence)
Ensembl Gene ModelENSMUSG00000022665 (Evidence)
Entrez Gene67896 (Evidence)
UniGene181074
DFCITC1575807, TC1587273
DoTSDT.99860269, DT.55100196
NIA Mouse Gene IndexU040810
Consensus CDS ProjectCCDS28192.1
International Mouse Knockout Project StatusCcdc80
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025346 VEGA Gene Model | MGI Sequence Detail 34264 C57BL/6J ±  kb
transcript OTTMUST00000062389 VEGA | MGI Sequence Detail 3671 Not Applicable 
polypeptide OTTMUSP00000030743 VEGA | MGI Sequence Detail 949 Not Applicable 

For the selected sequences
All sequences(49) RefSeq(10) UniProt(1)
Polymorphisms
SNPs within 2kb(310 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR025232 Domain of unknown function DUF4174
Protein Ontology PR:000005104 coiled-coil domain-containing protein 80
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:189183 Tremblay F, et al., Loss of coiled-coil domain containing 80 negatively modulates glucose homeostasis in diet-induced obese mice. Endocrinology. 2012 Sep;153(9):4290-303
All references(39)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory