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Fam45a Gene Detail
Summary
  • Symbol
    Fam45a
  • Name
    family with sequence similarity 45, member A
  • Synonyms
    1810055E12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915144
    NCBI Gene: 67894
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:60811585-60836227 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 56.52 cM, cytoband D3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    389 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915144
protein coding gene Chr19:60811449-60836235 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025296
protein coding gene Chr19:61418032-61446320 (+)
A/J MGP_AJ_G0025272
protein coding gene Chr19:58416581-58441855 (+)
AKR/J MGP_AKRJ_G0025241
protein coding gene Chr19:60238259-60266584 (+)
BALB/cJ MGP_BALBcJ_G0025267
protein coding gene Chr19:58501410-58525581 (+)
C3H/HeJ MGP_C3HHeJ_G0025027
protein coding gene Chr19:60480602-60511732 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025710
protein coding gene Chr19:62871633-62899792 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023122
protein coding gene Chr19:57247429-57267850 (+)
CAST/EiJ MGP_CASTEiJ_G0024492
protein coding gene Chr19:60588803-60612240 (+)
CBA/J MGP_CBAJ_G0025007
protein coding gene Chr19:65937263-65962420 (+)
DBA/2J MGP_DBA2J_G0025139
protein coding gene Chr19:58205035-58229354 (+)
FVB/NJ MGP_FVBNJ_G0025100
protein coding gene Chr19:57868329-57893926 (+)
LP/J MGP_LPJ_G0025225
protein coding gene Chr19:61251310-61275677 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025133
protein coding gene Chr19:65127528-65151063 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025768
protein coding gene Chr19:60484576-60508100 (+)
PWK/PhJ MGP_PWKPhJ_G0024240
protein coding gene Chr19:58143974-58169482 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024043
protein coding gene Chr19:59131487-59156672 (+)
WSB/EiJ MGP_WSBEiJ_G0024562
protein coding gene Chr19:60591111-60616211 (+)



Homology
more
  • Human Ortholog
    DENND10, DENN domain containing 10
  • Vertebrate Orthologs
    7
  • Human Ortholog
    DENND10, DENN domain containing 10
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FAM45A
  • Links
    NCBI Gene ID: 404636
    neXtProt AC: NX_Q8TCE6
    UniProt: Q8TCE6

  • Chr Location
    10q26.11; chr10:119104065-119137984 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024993 Ensembl Gene Model | MGI Sequence Detail 24643 C57BL/6J ±  kb
transcript ENSMUST00000025957 Ensembl | MGI Sequence Detail 2307 Not Applicable  
polypeptide ENSMUSP00000025957 Ensembl | MGI Sequence Detail 357 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 45
    cDNA 45

    Microarray probesets 3
References
more
  • Summaries
    All 24
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory