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Tmem100
Gene Detail
Symbol

Name
ID
Tmem100
transmembrane protein 100
MGI:1915138
Synonyms
1810057C19Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 11
54.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:90030348-90036508 bp, + strand
From VEGA annotation of GRCm38

  6161 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10110  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Tmem100

Human
homologs
Human Homolog TMEM100, transmembrane protein 100
NCBI Gene ID 55273
neXtProt AC  NX_Q9NV29
Human Chr (Location)  17q22; chr17:55719627-55732121 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Targeted(10)
Genomic Mutations involving Tmem100 (2)
 
Mice homozygous for a null mutations display prenatal lethality. Mice homozygous for one null mutation display defects in arterial differentiation and maturation and complete lethality during organogenesis.
 
Alleles Annotated to Human Diseases(1)    Phenotype Images(4)
Interactions
Tmem100 interacts with 99 markers (Mir1b, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (25 annotations)
Process angiogenesis, arterial endothelial cell differentiation, ...
Component cytoplasm, endoplasmic reticulum, ...
Function molecular_function
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (10 records)
Data Summary: Results (367)    Tissues (197)    Images (49)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 350
In situ reporter (knock in) 17
cDNA source data(16)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(16) cDNA(16)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000001282 (Evidence)
Ensembl Gene ModelENSMUSG00000069763 (Evidence)
Entrez Gene67888 (Evidence)
UniGene212428
DFCITC1590278, TC1583761
DoTSDT.101707538, DT.50316071
NIA Mouse Gene IndexU013179
Consensus CDS ProjectCCDS25239.1
International Mouse Knockout Project StatusTmem100
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001282 VEGA Gene Model | MGI Sequence Detail 6161 C57BL/6J ±  kb
transcript OTTMUST00000002554 VEGA | MGI Sequence Detail 1767 Not Applicable 
polypeptide OTTMUSP00000001262 VEGA | MGI Sequence Detail 134 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(6) UniProt(1)
Polymorphisms
SNPs within 2kb(124 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000030673 transmembrane protein 100
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:201363 Eisenman ST, et al., Distribution of TMEM100 in the mouse and human gastrointestinal tract--a novel marker of enteric nerves. Neuroscience. 2013 Jun 14;240:117-28
All references(37)
Other
accession IDs
MGI:2144451

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory