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Mtln Gene Detail
Summary
  • Symbol
    Mtln
  • Name
    mitoregulin
  • Synonyms
    1500011K16Rik
Location & Maps
more
  • Sequence Map
    Chr2:127791388-127792488 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1101 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 62.10 cM
  • Mapping Data
    1 experiment
Homology
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Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit abnormal mitrochondrial respiratory complex formation and calcium retention capacity.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    • All Sequences
    • RefSeq
    • UniProt
    • UniGene
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000016098 VEGA Gene Model | MGI Sequence Detail 1101 C57BL/6J ±  kb
    transcript OTTMUST00000038459 VEGA | MGI Sequence Detail 800 Not Applicable  
    polypeptide OTTMUSP00000068292 VEGA | MGI Sequence Detail 56 Not Applicable  
    For the selected sequence
    Polymorphisms
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    • SNPs within 2kb
      20 from dbSNP Build 142
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • InterPro Domains
      IPR038778 Mitoregulin
    Molecular
    Reagents
    less
    • All nucleic 26
      cDNA 26

      Microarray probesets 3
    References
    more
    • Summaries
      All 24
      Developmental Gene Expression 2
      Gene Ontology 2
      Phenotypes 6
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:263464 Stein CS, et al., Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency. Cell Rep. 2018 Jun 26;23(13):3710-3720.e8

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    10/16/2018
    MGI 6.12
    The Jackson Laboratory