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Mri1 Gene Detail
Summary
  • Symbol
    Mri1
  • Name
    methylthioribose-1-phosphate isomerase 1
  • Synonyms
    2410018C20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915123
    NCBI Gene: 67873
  • Gene Overview
    MyGene.info: MRI1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:84250576-84257324 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 40.74 cM, cytoband C3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    73 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915123
protein coding gene Chr8:84249906-84257326 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033861
protein coding gene Chr8:85130343-85137759 (-)
A/J MGP_AJ_G0033844
protein coding gene Chr8:81794872-81802230 (-)
AKR/J MGP_AKRJ_G0033770
protein coding gene Chr8:84219477-84226893 (-)
BALB/cJ MGP_BALBcJ_G0033837
protein coding gene Chr8:81901740-81909156 (-)
C3H/HeJ MGP_C3HHeJ_G0033547
protein coding gene Chr8:84825015-84832373 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034357
protein coding gene Chr8:88394025-88401445 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031299
protein coding gene Chr8:75591083-75598517 (-)
CAST/EiJ MGP_CASTEiJ_G0032877
protein coding gene Chr8:84246168-84253546 (-)
CBA/J MGP_CBAJ_G0033523
protein coding gene Chr8:91492712-91500125 (-)
DBA/2J MGP_DBA2J_G0033677
protein coding gene Chr8:81432298-81439656 (-)
FVB/NJ MGP_FVBNJ_G0033624
protein coding gene Chr8:80367584-80376058 (-)
LP/J MGP_LPJ_G0033768
protein coding gene Chr8:85242523-85249939 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033666
protein coding gene Chr8:94009963-94017379 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034374
protein coding gene Chr8:84191597-84199017 (-)
PWK/PhJ MGP_PWKPhJ_G0032581
protein coding gene Chr8:80658551-80665961 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032417
protein coding gene Chr8:83008375-83016447 (-)
WSB/EiJ MGP_WSBEiJ_G0032990
protein coding gene Chr8:84604512-84611928 (-)



Homology
more
  • Human Ortholog
    MRI1, methylthioribose-1-phosphate isomerase 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MRI1, methylthioribose-1-phosphate isomerase 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    M1Pi, MRDI, MTNA, Ypr118w
  • Links
    NCBI Gene ID: 84245
    neXtProt AC: NX_Q9BV20
    UniProt: Q9BV20

  • Chr Location
    19p13.13; chr19:13764492-13774282 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 7160
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: MRI1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    30 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Gene trapped
    6
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Mri1
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 67873 NCBI Gene Model | MGI Sequence Detail 6749 C57BL/6J ±  kb
transcript NM_026423 RefSeq | MGI Sequence Detail 2149 C57BL/6  
polypeptide Q9CQT1 UniProt | EBI | MGI Sequence Detail 369 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 29
    cDNA 28
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 54
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 30
  • Earliest
    J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54:113-145
  • Latest
    J:266142 Grosjean F, et al., Pharmacologic control of oxidative stress and inflammation determines whether diabetic glomerulosclerosis progresses or decreases: A pilot study in sclerosis-prone mice. PLoS One. 2018;13(9):e0204366

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory