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Nsmce4a Gene Detail
Summary
  • Symbol
    Nsmce4a
  • Name
    NSE4 homolog A, SMC5-SMC6 complex component
  • Synonyms
    2410003A14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915122
    NCBI Gene: 67872
  • Gene Overview
    MyGene.info: NSMCE4A
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:130532523-130547412 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 73.19 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    126 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915122
protein coding gene Chr7:130532523-130573118 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033092
protein coding gene Chr7:135055210-135097149 (-)
A/J MGP_AJ_G0033074
protein coding gene Chr7:131380244-131422304 (-)
AKR/J MGP_AKRJ_G0033006
protein coding gene Chr7:134861527-134903137 (-)
BALB/cJ MGP_BALBcJ_G0033075
protein coding gene Chr7:131054149-131096653 (-)
C3H/HeJ MGP_C3HHeJ_G0032789
protein coding gene Chr7:134733474-134775826 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033585
protein coding gene Chr7:140264908-140305278 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030557
protein coding gene Chr7:132540342-132581376 (-)
CAST/EiJ MGP_CASTEiJ_G0032119
protein coding gene Chr7:126546983-126586338 (-)
CBA/J MGP_CBAJ_G0032762
protein coding gene Chr7:145052304-145098006 (-)
DBA/2J MGP_DBA2J_G0032914
protein coding gene Chr7:129382405-129424079 (-)
FVB/NJ MGP_FVBNJ_G0032867
protein coding gene Chr7:129232058-129272909 (-)
LP/J MGP_LPJ_G0033008
protein coding gene Chr7:136535678-136576235 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032899
protein coding gene Chr7:146013175-146058860 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033604
protein coding gene Chr7:133798764-133844427 (-)
PWK/PhJ MGP_PWKPhJ_G0031825
protein coding gene Chr7:122445317-122485375 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031671
protein coding gene Chr7:120622180-120664508 (-)
WSB/EiJ MGP_WSBEiJ_G0032230
protein coding gene Chr7:134801556-134840601 (-)



Homology
more
  • Human Ortholog
    NSMCE4A, NSE4 homolog A, SMC5-SMC6 complex component
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NSMCE4A, NSE4 homolog A, SMC5-SMC6 complex component
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C10orf86, NS4EA, NSE4A
  • Links
    NCBI Gene ID: 54780
    neXtProt AC: NX_Q9NXX6
    UniProt: Q9NXX6

  • Chr Location
    10q26.13; chr10:121957088-121975228 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67872 NCBI Gene Model | MGI Sequence Detail 14890 C57BL/6J ±  kb
transcript NM_001162855 RefSeq | MGI Sequence Detail 1484 C57BL/6  
polypeptide NP_001156327 RefSeq | MGI Sequence Detail 381 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR014854 Non-structural maintenance of chromosome element 4, C-terminal
    IPR027786 Nse4/EID family
    IPR029225 Nse4/EID protein, Nse3/MAGE-binding domain
Molecular
Reagents
less
  • All nucleic 109
    cDNA 109

    Microarray probesets 3
References
more
  • Summaries
    All 21
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory