About   Help   FAQ
Paip2 Gene Detail
Summary
  • Symbol
    Paip2
  • Name
    polyadenylate-binding protein-interacting protein 2
  • Synonyms
    2310050K10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915119
    NCBI Gene: 67869
  • Gene Overview
    MyGene.info: PAIP2
Location & Maps
more
  • Sequence Map
    Chr18:35598617-35617186 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      18570 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 19.16 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PAIP2, poly(A) binding protein interacting protein 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    PAIP2, poly(A) binding protein interacting protein 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    PAIP-2, PAIP2A
  • Links
    NCBI Gene ID: 51247
    neXtProt AC: NX_Q9BPZ3

  • Chr Location
    5q31.2; chr5:139341832-139369720 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    14 phenotypes from multigenic genotypes
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    93
  • Gene trapped
    89
  • Targeted
    4
Mice homozygous for a knock-out allele exhibit male infertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023945 VEGA Gene Model | MGI Sequence Detail 18570 C57BL/6J ±  kb
transcript OTTMUST00000058516 VEGA | MGI Sequence Detail 713 Not Applicable  
polypeptide OTTMUSP00000028357 VEGA | MGI Sequence Detail 124 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    49 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000012237 polyadenylate-binding protein-interacting protein 2
  • InterPro Domains
    IPR009818 Ataxin-2, C-terminal
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 5
Other
Accession IDs
less
MGI:2147330
References
more
  • Summaries
    All 37
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:197896 Khoutorsky A, et al., Control of synaptic plasticity and memory via suppression of poly(A)-binding protein. Neuron. 2013 Apr 24;78(2):298-311

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/12/2016
MGI 6.04
The Jackson Laboratory