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Paip2
Gene Detail
 Symbol
Name
ID
Paip2
polyadenylate-binding protein-interacting protein 2
MGI:1915119
Synonyms 2310050K10Rik
Feature Type protein coding gene
Genetic Map
Chromosome 18
19.16 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:35598617-35617186 bp, + strand
From VEGA annotation of GRCm38

  18570 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22978  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Paip2

Human
homologs
Human Homolog PAIP2, poly(A) binding protein interacting protein 2
NCBI Gene ID 51247
neXtProt AC  NX_Q9BPZ3
Human Synonyms  PAIP-2, PAIP2A
Human Chr (Location)  5q31.2; chr5:139341832-139369720 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(93) : Gene trapped(89) Targeted(4)
 
Mice homozygous for a knock-out allele exhibit male infertility.
 
Interactions
Paip2 interacts with 230 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process memory, negative regulation of translation, ...
Component cytoplasm
Function mRNA binding, poly(A) binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (1)    Tissues (1)    Images (1)
Theiler Stages: 23
Assay TypeResults
RNA in situ 1
cDNA source data(15)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(15) cDNA(15)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000023945 (Evidence)
Ensembl Gene ModelENSMUSG00000037058 (Evidence)
Entrez Gene67869 (Evidence)
DFCITC1572286, TC1665659
DoTSDT.101241596, DT.101260349, DT.110755563, DT.535631, DT.55211532, DT.99862130, DT.99862134
Consensus CDS ProjectCCDS29143.1
International Mouse Knockout Project StatusPaip2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023945 VEGA Gene Model | MGI Sequence Detail 18570 C57BL/6J ±  kb
transcript OTTMUST00000058515 VEGA | MGI Sequence Detail 1475 Not Applicable 
polypeptide OTTMUSP00000028356 VEGA | MGI Sequence Detail 124 Not Applicable 

For the selected sequences
All sequences(57) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(49 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009818 Ataxin-2, C-terminal
Protein Ontology PR:000012237 polyadenylate-binding protein-interacting protein 2
References (Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:197896 Khoutorsky A, et al., Control of synaptic plasticity and memory via suppression of poly(A)-binding protein. Neuron. 2013 Apr 24;78(2):298-311
All references(40)
Other
accession IDs
MGI:2147330

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory