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Cela3b
Gene Detail
 Symbol
Name
ID
Cela3b
chymotrypsin-like elastase family, member 3B
MGI:1915118
Synonyms 0910001F22Rik, 2310074F01Rik, Ela3, Ela3b
Feature Type protein coding gene
Genetic Map
Chromosome 4
69.90 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:137420999-137430540 bp, - strand
From VEGA annotation of GRCm38

  9542 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:128227  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: trypsin
Gene Tree: Cela3b

Human
homologs
Human Homolog CELA3B, chymotrypsin-like elastase family, member 3B
NCBI Gene ID 23436
neXtProt AC  NX_P08861
Human Synonyms  CBPP, E1, EL-1, ELA3B
Human Chr (Location)  1p36.12; chr1:21976925-21989354 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(1) Targeted(1)
Incidental mutations (data from APF )
Interactions
Cela3b interacts with 10 markers (Mir30a, Mir30d, Mir30e, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process proteolysis
Component cellular_component
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (6)    Tissues (3)    Images (6)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 6
cDNA source data(317)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(319) cDNA(318) Other(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000009879 (Evidence)
Ensembl Gene ModelENSMUSG00000023433 (Evidence)
Entrez Gene67868 (Evidence)
UniGene297477
NIA Mouse Gene IndexU025680
EC3.4.21.70
Consensus CDS ProjectCCDS18817.1
International Mouse Knockout Project StatusCela3b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009879 VEGA Gene Model | MGI Sequence Detail 9542 C57BL/6J ±  kb
transcript OTTMUST00000022898 VEGA | MGI Sequence Detail 926 Not Applicable 
polypeptide OTTMUSP00000010452 VEGA | MGI Sequence Detail 269 Not Applicable 

For the selected sequences
All sequences(21) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(416 from dbSNP Build 137)    SNPs within 2kb including multiple locations(460)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000007013 chymotrypsin-like elastase family member 3B
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:183127 Westmoreland JJ, et al., Pancreas-specific deletion of prox1 affects development and disrupts homeostasis of the exocrine pancreas. Gastroenterology. 2012 Apr;142(4):999-1009.e6
All references(36)
Other
accession IDs
MGI:1923522, MGI:2140315

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory