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Cela3b Gene Detail
Summary
  • Symbol
    Cela3b
  • Name
    chymotrypsin-like elastase family, member 3B
  • Synonyms
    0910001F22Rik, 2310074F01Rik, Ela3, Ela3b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915118
    NCBI Gene: 67868
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:137421008-137430520 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 69.90 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    354 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915118
protein coding gene Chr4:137420999-137430540 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028981
protein coding gene Chr4:140045985-140055914 (-)
A/J MGP_AJ_G0028940
protein coding gene Chr4:134093460-134107289 (-)
AKR/J MGP_AKRJ_G0028892
protein coding gene Chr4:137948185-137957839 (-)
BALB/cJ MGP_BALBcJ_G0028964
protein coding gene Chr4:134777316-134785888 (-)
C3H/HeJ MGP_C3HHeJ_G0028678
protein coding gene Chr4:138247581-138264256 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029405
protein coding gene Chr4:144999784-145008575 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026676
protein coding gene Chr4:127100625-127109434 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0028643
protein coding gene Chr4:149093899-149106732 (-)
DBA/2J MGP_DBA2J_G0028792
protein coding gene Chr4:134492147-134499665 (-)
FVB/NJ MGP_FVBNJ_G0028759
protein coding gene Chr4:133453893-133491907 (-)
LP/J MGP_LPJ_G0028891
protein coding gene Chr4:140101049-140140181 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028785
protein coding gene Chr4:153161312-153175833 (-)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0027830
protein coding gene Chr4:131313140-131321019 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027656
protein coding gene Chr4:134199890-134208160 (-)
WSB/EiJ MGP_WSBEiJ_G0028188
protein coding gene Chr4:138585239-138595782 (-)



Homology
more
  • Human Ortholog
    CELA3A, chymotrypsin like elastase family member 3A
  • Vertebrate Orthologs
    12
  • Human Ortholog
    CELA3A, chymotrypsin like elastase family member 3A
    Orthology source: HGNC
  • Synonyms
    ELA3, ELA3A
  • Links
    NCBI Gene ID: 10136
    neXtProt AC: NX_P09093
    UniProt: P09093

  • Chr Location
    1p36.12; chr1:22001656-22012542 (+)  GRCh38.p7

  • Human Ortholog
    CELA3B, chymotrypsin like elastase family member 3B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CBPP, ELA3B
  • Links
    NCBI Gene ID: 23436
    neXtProt AC: NX_P08861
    UniProt: P08861

  • Chr Location
    1p36.12; chr1:21976894-21989354 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    2
  • Gene trapped
    1
  • Targeted
    2
  • Genomic Mutations
    3 involving Cela3b
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 67868 NCBI Gene Model | MGI Sequence Detail 9513 C57BL/6J ±  kb
transcript NM_026419 RefSeq | MGI Sequence Detail 897 C57BL/6  
polypeptide Q9CQ52 UniProt | EBI | MGI Sequence Detail 269 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • EC
  • InterPro Domains
    IPR001314 Peptidase S1A, chymotrypsin family
    IPR009003 Peptidase S1, PA clan
    IPR001254 Serine proteases, trypsin domain
    IPR018114 Serine proteases, trypsin family, histidine active site
    IPR033116 Serine proteases, trypsin family, serine active site
Molecular
Reagents
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  • All nucleic 320
    cDNA 319
    Other 1

    Microarray probesets 5
Other
Accession IDs
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MGI:1923522, MGI:2140315
References
more
  • Summaries
    All 37
    Developmental Gene Expression 6
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265607 Naba A, et al., Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression. Sci Rep. 2017 Jan 10;7:40495

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory