Cela3b
Gene Detail

Symbol Name ID

Cela3b chymotrypsin-like elastase family, member 3B MGI:1915118

Synonyms

0910001F22Rik, 2310074F01Rik, Ela3, Ela3b

Feature Type

protein coding gene

Genetic Map

Chromosome 4

69.90 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr4:137420999-137430540 bp, - strand From VEGA annotation of GRCm38   9542 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:128227  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: trypsin
Gene Tree: Cela3b

Human homologs

Human Homolog		CELA3B, chymotrypsin-like elastase family, member 3B
NCBI Gene ID		23436
neXtProt AC		NX_P08861
Human Synonyms		CBPP, E1, EL-1, ELA3B
Human Chr (Location)		1p36.12; chr1:22303418-22315847 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(2) : Targeted(1) Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	proteolysis
Component	cellular_component
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (6)    Tissues (3)    Images (6)
Theiler Stages: 22, 23

Assay Type	Results
RNA in situ	6

cDNA source data(316)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(318) cDNA(317) Other(1)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000009879 (Evidence)
Ensembl Gene Model	ENSMUSG00000023433 (Evidence)
Entrez Gene	67868 (Evidence)
UniGene	297477
NIA Mouse Gene Index	U025680
EC	3.4.21.70
Consensus CDS Project	CCDS18817.1
International Mouse Knockout Project Status	Cela3b

Sequences

Length	Strain/Species
genomic	OTTMUSG00000009879	VEGA Gene Model | MGI Sequence Detail	9542	C57BL/6J
transcript	OTTMUST00000022898	VEGA | MGI Sequence Detail	926	Not Applicable
polypeptide	OTTMUSP00000010452	VEGA | MGI Sequence Detail	269	Not Applicable

All sequences(21) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(300 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001254	Peptidase S1
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR018114	Peptidase S1, trypsin family, active site
InterPro	IPR009003	Trypsin-like cysteine/serine peptidase domain
Protein Ontology	PR:000007013	elastase-3B

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:183127 Westmoreland JJ, et al., Pancreas-specific deletion of prox1 affects development and disrupts homeostasis of the exocrine pancreas. Gastroenterology. 2012 Apr;142(4):999-1009.e6
All references(36)

Other accession IDs

MGI:1923522, MGI:2140315