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Slc25a11 Gene Detail
Summary
  • Symbol
    Slc25a11
  • Name
    solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11
  • Synonyms
    2310022P18Rik, 2oxoc
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915113
    NCBI Gene: 67863
  • Gene Overview
    MyGene.info: SLC25A11
Location & Maps
more
  • Sequence Map
    Chr11:70644196-70647479 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3284 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 43.21 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SLC25A11, solute carrier family 25 member 11
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SLC25A11, solute carrier family 25 member 11
    Orthology source: HGNC, HomoloGene
  • Synonyms
    OGC, SLC20A4
  • Links
    NCBI Gene ID: 8402
    neXtProt AC: NX_Q02978

  • Chr Location
    17p13.3; chr17:4937130-4940167 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Slc25a11
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006069 VEGA Gene Model | MGI Sequence Detail 3284 C57BL/6J ±  kb
transcript OTTMUST00000013683 VEGA | MGI Sequence Detail 1711 Not Applicable  
polypeptide OTTMUSP00000006344 VEGA | MGI Sequence Detail 314 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    40 from dbSNP Build 142
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000015006 mitochondrial 2-oxoglutarate/malate carrier protein
  • InterPro Domains
    IPR023395 Mitochondrial carrier domain
    IPR018108 Mitochondrial substrate/solute carrier
Molecular
Reagents
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  • All nucleic 12
    Genomic 2
    cDNA 9
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory