Ppp6c
Gene Detail

Symbol Name ID

Ppp6c protein phosphatase 6, catalytic subunit MGI:1915107

Synonyms

2310003C10Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 2

24.44 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr2:39194354-39226451 bp, - strand From VEGA annotation of GRCm38   32098 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:68273  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: serine/threonine-protein phosphatase, conventional type
Gene Tree: Ppp6c

Human homologs

Human Homolog		PPP6C, protein phosphatase 6, catalytic subunit
NCBI Gene ID		5537
neXtProt AC		NX_O00743
Human Synonyms		PP6, PP6C
Human Chr (Location)		9q33.3; chr9:127908852-127952218 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(42) : Targeted(2) Gene trapped(40)

Gene Ontology (GO) classifications

All GO classifications: (12 annotations)

Process	cell cycle, protein dephosphorylation
Component	cytoplasm, cytosol
Function	hydrolase activity, metal ion binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (30)    Tissues (30)    Images (9)
Theiler Stages: 19, 22, 23, 28

Assay Type	Results
RNA in situ	30

cDNA source data(8)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(8) cDNA(8)
Microarray probesets(6)

Other database links

VEGA Gene Model	OTTMUSG00000012451 (Evidence)
Ensembl Gene Model	ENSMUSG00000026753 (Evidence)
Entrez Gene	67857 (Evidence)
DFCI	TC1576640, TC1722327
DoTS	DT.101389012, DT.530512, DT.94352751
NIA Mouse Gene Index	U022578
EC	3.1.3.16
Consensus CDS Project	CCDS16017.1
International Mouse Knockout Project Status	Ppp6c

Sequences

Length	Strain/Species
genomic	OTTMUSG00000012451	VEGA Gene Model | MGI Sequence Detail	32098	C57BL/6J
transcript	OTTMUST00000029606	VEGA | MGI Sequence Detail	4115	Not Applicable
polypeptide	OTTMUSP00000013324	VEGA | MGI Sequence Detail	305	Not Applicable

All sequences(30) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(47 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR004843	Metallophosphoesterase domain
InterPro	IPR006186	Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
Protein Ontology	PR:000013158	serine/threonine-protein phosphatase 6 catalytic subunit

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(35)