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Ppp6c
Gene Detail
Symbol

Name
ID
Ppp6c
protein phosphatase 6, catalytic subunit
MGI:1915107
Synonyms
2310003C10Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 2
24.44 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:39194354-39226451 bp, - strand
From VEGA annotation of GRCm38

  32098 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68273  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PPP6C
Protein SuperFamily: serine/threonine-protein phosphatase, conventional type
Gene Tree: Ppp6c

Human
homologs
PPP6C, protein phosphatase 6, catalytic subunit
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 5537
neXtProt AC: NX_O00743

Human Synonyms: PP6, PP6C

Human Chr (Location): 9q33.3; chr9:125146573-125189939 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(43) : Gene trapped(40) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ppp6c interacts with 410 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell cycle, protein dephosphorylation
Component cytoplasm, cytosol
Function hydrolase activity, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (30)    Tissues (30)    Images (9)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 30
cDNA source data(8)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase ppp6c ; ZFIN ppp6c    NEW 
Molecular
reagents
All nucleic(8) cDNA(8)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000012451 (Evidence)
Ensembl Gene Model ENSMUSG00000026753 (Evidence)
Entrez Gene 67857 (Evidence)
DFCI TC1576640, TC1722327
DoTS DT.101389012, DT.530512, DT.94352751
NIA Mouse Gene Index U022578
EC 3.1.3.16
Consensus CDS Project CCDS16017.1
International Mouse Phenotyping Consortium Status Ppp6c
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000012451 VEGA Gene Model | MGI Sequence Detail 32098 C57BL/6J ±  kb
transcript OTTMUST00000029606 VEGA | MGI Sequence Detail 4115 Not Applicable 
polypeptide OTTMUSP00000013324 VEGA | MGI Sequence Detail 305 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(59 from dbSNP Build 137)    SNPs within 2kb including multiple locations(61)
Protein-related
information
ResourceIDDescription
InterPro IPR004843 Calcineurin-like phosphoesterase domain, apaH type
InterPro IPR029052 Metallo-dependent phosphatase-like
InterPro IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
Protein Ontology PR:000013158 serine/threonine-protein phosphatase 6 catalytic subunit
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(36)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory