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Ppp6c
Gene Detail
 Symbol
Name
ID
Ppp6c
protein phosphatase 6, catalytic subunit
MGI:1915107
Synonyms 2310003C10Rik
Feature Type protein coding gene
Genetic Map
Chromosome 2
24.44 cM, cytoband B
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:39194354-39226451 bp, - strand
From VEGA annotation of GRCm38

  32098 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68273  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: serine/threonine-protein phosphatase, conventional type
Gene Tree: Ppp6c

Human
homologs
Human Homolog PPP6C, protein phosphatase 6, catalytic subunit
NCBI Gene ID 5537
neXtProt AC  NX_O00743
Human Synonyms  PP6, PP6C
Human Chr (Location)  9q33.3; chr9:125146573-125189939 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(43) : Gene trapped(40) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ppp6c interacts with 410 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process cell cycle, protein dephosphorylation
Component cytoplasm, cytosol
Function hydrolase activity, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (30)    Tissues (30)    Images (9)
Theiler Stages: 19, 22, 23, 28
Assay TypeResults
RNA in situ 30
cDNA source data(8)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(8) cDNA(8)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000012451 (Evidence)
Ensembl Gene ModelENSMUSG00000026753 (Evidence)
Entrez Gene67857 (Evidence)
DFCITC1576640, TC1722327
DoTSDT.101389012, DT.530512, DT.94352751
NIA Mouse Gene IndexU022578
EC3.1.3.16
Consensus CDS ProjectCCDS16017.1
International Mouse Knockout Project StatusPpp6c
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000012451 VEGA Gene Model | MGI Sequence Detail 32098 C57BL/6J ±  kb
transcript OTTMUST00000029606 VEGA | MGI Sequence Detail 4115 Not Applicable 
polypeptide OTTMUSP00000013324 VEGA | MGI Sequence Detail 305 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(59 from dbSNP Build 137)    SNPs within 2kb including multiple locations(61)
Protein-related
information
ResourceIDDescription
InterPro IPR004843 Metallophosphoesterase domain
InterPro IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
Protein Ontology PR:000013158 serine/threonine-protein phosphatase 6 catalytic subunit
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(37)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory