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Asprv1 Gene Detail
Summary
  • Symbol
    Asprv1
  • Name
    aspartic peptidase, retroviral-like 1
  • Synonyms
    2300003P22Rik, SASP, SASPase, Taps, TPA-induced aspartic proteinase-like
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915105
    NCBI Gene: 67855
Location & Maps
more
  • Sequence Map
    Chr6:86628164-86629710 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1547 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 37.75 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    ASPRV1, aspartic peptidase, retroviral-like 1
  • Vertebrate Orthologs
    5
  • Human Ortholog
    ASPRV1, aspartic peptidase, retroviral-like 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MUNO, SASP, SASPase, Taps
  • Links
    NCBI Gene ID: 151516
    neXtProt AC: NX_Q53RT3

  • Chr Location
    2p13.3; chr2:69960089-69962265 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    1 images
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    2
  • Spontaneous
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Asprv1
  • Incidental Mutations
Mice homozygous for a targeted null allele develop fine skin wrinkles at the side of their body without any apparent epidermal differentiation defect.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000056543 VEGA Gene Model | MGI Sequence Detail 1547 C57BL/6J ±  kb
transcript OTTMUST00000139668 VEGA | MGI Sequence Detail 1547 Not Applicable  
polypeptide OTTMUSP00000073257 VEGA | MGI Sequence Detail 339 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    35 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000004383 retroviral-like aspartic protease 1
  • EC
  • InterPro Domains
    IPR001969 Aspartic peptidase, active site
    IPR021109 Aspartic peptidase domain
    IPR001995 Peptidase A2A, retrovirus, catalytic
Molecular
Reagents
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  • All nucleic 58
    cDNA 58

    Microarray probesets 3
Other
Accession IDs
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MGI:1889382
References
more
  • Summaries
    All 27
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory