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Asprv1
Gene Detail
 Symbol
Name
ID
Asprv1
aspartic peptidase, retroviral-like 1
MGI:1915105
Synonyms 2300003P22Rik, SASP, SASPase, Taps, TPA-induced aspartic proteinase-like
Feature Type protein coding gene
Genetic Map
Chromosome 6
37.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr6:86628174-86629702 bp, + strand
From Ensembl annotation of GRCm38

  1529 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23582  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle

Gene Tree: Asprv1

Human
homologs
Human Homolog ASPRV1, aspartic peptidase, retroviral-like 1
NCBI Gene ID 151516
neXtProt AC  NX_Q53RT3
Human Synonyms  MUNO, SASP, SASPase, Taps
Human Chr (Location)  2p13.3; chr2:69960089-69962265 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a targeted null allele develop fine skin wrinkles at the side of their body without any apparent epidermal differentiation defect.
 
Phenotype Images(1)
Interactions
Asprv1 interacts with 55 markers (Mir22, Mir31, Mir134, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process protein processing, proteolysis, ...
Component integral component of membrane, membrane
Function aspartic endopeptidase activity, intramembrane cleaving, aspartic-type endopeptidase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (7)    Tissues (2)    Images (6)
Theiler Stages: 23
Assay TypeResults
RNA in situ 7
cDNA source data(58)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(58) cDNA(58)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000033508 (Evidence)
Entrez Gene67855 (Evidence)
UniGene183043
DFCITC1580639, TC1598819
DoTSDT.536539
NIA Mouse Gene IndexU007122
EC3.4.23.-
Consensus CDS ProjectCCDS39542.1
International Mouse Knockout Project StatusAsprv1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033508 Ensembl Gene Model | MGI Sequence Detail 1529 C57BL/6J ±  kb
transcript ENSMUST00000043400 Ensembl | MGI Sequence Detail 1529 Not Applicable 
polypeptide ENSMUSP00000046121 Ensembl | MGI Sequence Detail 339 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(35 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR021109 Aspartic peptidase
InterPro IPR001995 Peptidase A2A, retrovirus, catalytic
InterPro IPR001969 Peptidase aspartic, active site
Protein Ontology PR:000004383 retroviral-like aspartic protease 1
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(29)
Other
accession IDs
MGI:1889382

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory