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Sncaip Gene Detail
Summary
  • Symbol
    Sncaip
  • Name
    synuclein, alpha interacting protein (synphilin)
  • Synonyms
    4933427B05Rik, synphilin-1, SYPH1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915097
    NCBI Gene: 67847
  • Gene Overview
    MyGene.info: SNCAIP
Location & Maps
more
  • Sequence Map
    Chr18:52767709-52915935 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      148227 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 28.27 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SNCAIP, synuclein alpha interacting protein
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SNCAIP, synuclein alpha interacting protein
    Orthology source: HGNC, HomoloGene
  • Synonyms
    Sph1, SYPH1
  • Links
    NCBI Gene ID: 9627
    neXtProt AC: NX_Q9Y6H5

  • Chr Location
    5q23.2; chr5:122311349-122464099 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human SNCAIP associations

Human Disease Mouse Models
       Parkinson Disease, Late-Onset; PD   OMIM: 168600
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042341 VEGA Gene Model | MGI Sequence Detail 148227 C57BL/6J ±  kb
transcript OTTMUST00000111559 VEGA | MGI Sequence Detail 3724 Not Applicable  
polypeptide OTTMUSP00000062485 VEGA | MGI Sequence Detail 965 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    677 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    Genomic 1
    cDNA 12
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1918444, MGI:2147384
References
more
  • Summaries
    All 36
    Developmental Gene Expression 5
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:177885 Brunskill EW, et al., Defining the molecular character of the developing and adult kidney podocyte. PLoS One. 2011;6(9):e24640

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory