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Sncaip
Gene Detail
Symbol

Name
ID
Sncaip
synuclein, alpha interacting protein (synphilin)
MGI:1915097
Synonyms
4933427B05Rik, synphilin-1, SYPH1
Feature Type
protein coding gene
Genetic Map
Chromosome 18
28.27 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:52767709-52915935 bp, + strand
From VEGA annotation of GRCm38

  148227 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3987  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Sncaip

Human
homologs
Human Homolog SNCAIP, synuclein, alpha interacting protein
NCBI Gene ID 9627
neXtProt AC  NX_Q9Y6H5
Human Synonyms  Sph1, SYPH1
Human Chr (Location)  5q23.2; chr5:122311558-122464099 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human SNCAIP
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Sncaip interacts with 321 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process dopamine metabolic process, regulation of inclusion body assembly, ...
Component cytoplasm
Function identical protein binding, ubiquitin protein ligase binding
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (81)    Tissues (81)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 79
RT-PCR 2
cDNA source data(12)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(14) Genomic(1) cDNA(12) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000042341 (Evidence)
Ensembl Gene ModelENSMUSG00000024534 (Evidence)
Entrez Gene67847 (Evidence)
DFCITC1594184, TC1629830, TC1595740, TC1582485
DoTSDT.101707241, DT.91323095, DT.55283036, DT.101723844, DT.55238197, DT.94185476
Consensus CDS ProjectCCDS37820.2, CCDS57124.1
International Mouse Knockout Project StatusSncaip
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042341 VEGA Gene Model | MGI Sequence Detail 148227 C57BL/6J ±  kb
transcript OTTMUST00000111559 VEGA | MGI Sequence Detail 3724 Not Applicable 
polypeptide OTTMUSP00000062485 VEGA | MGI Sequence Detail 965 Not Applicable 

For the selected sequences
All sequences(112) RefSeq(12) UniProt(27)
Polymorphisms
SNPs within 2kb(683 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002110 Ankyrin repeat
InterPro IPR020683 Ankyrin repeat-containing domain
Protein Ontology PR:000015323 synphilin-1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:177885 Brunskill EW, et al., Defining the molecular character of the developing and adult kidney podocyte. PLoS One. 2011;6(9):e24640
All references(40)
Other
accession IDs
MGI:1918444, MGI:2147384

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory