Sncaip
Gene Detail

Symbol Name ID

Sncaip synuclein, alpha interacting protein (synphilin) MGI:1915097

Synonyms

4933427B05Rik, synphilin-1, SYPH1

Feature Type

protein coding gene

Genetic Map

Chromosome 18

28.27 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr18:52767709-52915935 bp, + strand From VEGA annotation of GRCm38   148227 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:3987  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Sncaip

Human homologs

Human Homolog		SNCAIP, synuclein, alpha interacting protein
NCBI Gene ID		9627
neXtProt AC		NX_Q9Y6H5
Human Synonyms		Sph1, SYPH1
Human Chr (Location)		5q23.2; chr5:121647820-121799794 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human SNCAIP

Alleles and phenotypes

All alleles(4) : Targeted(3) Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (7 annotations)

Process	dopamine metabolic process, regulation of inclusion body assembly, ...
Component	cytoplasm, nucleolus, ...
Function	ubiquitin protein ligase binding

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (81)    Tissues (81)    Images (2)
Theiler Stages: 14, 15, 17, 19, 23, 28

Assay Type	Results
RNA in situ	79
RT-PCR	2

cDNA source data(12)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(14) Genomic(1) cDNA(12) Primer pair(1)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000042341 (Evidence)
Ensembl Gene Model	ENSMUSG00000024534 (Evidence)
Entrez Gene	67847 (Evidence)
DFCI	TC1582485, TC1594184, TC1595740, TC1629830
DoTS	DT.101707241, DT.101723844, DT.55238197, DT.55283036, DT.91323095, DT.94185476
Consensus CDS Project	CCDS37820.2, CCDS57124.1
International Mouse Knockout Project Status	Sncaip

Sequences

Length	Strain/Species
genomic	OTTMUSG00000042341	VEGA Gene Model | MGI Sequence Detail	148227	C57BL/6J
transcript	OTTMUST00000111559	VEGA | MGI Sequence Detail	3724	Not Applicable
polypeptide	OTTMUSP00000062485	VEGA | MGI Sequence Detail	965	Not Applicable

All sequences(97) RefSeq(8) UniProt(16)

Polymorphisms

SNPs(618 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002110	Ankyrin repeat
InterPro	IPR020683	Ankyrin repeat-containing domain
Protein Ontology	PR:000015323	synphilin-1

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:177885 Brunskill EW, et al., Defining the molecular character of the developing and adult kidney podocyte. PLoS One. 2011;6(9):e24640
All references(38)

Other accession IDs

MGI:1918444, MGI:2147384