Nmral1 MGI Mouse Gene Detail - MGI:1915074 - NmrA-like family domain containing 1

Symbol

Nmral1
Name

NmrA-like family domain containing 1
Synonyms

1110025F24Rik

Feature Type

protein coding gene
IDs

MGI:1915074
NCBI Gene: 67824
Alliance

genome feature page
Transcription Start Sites

4 TSS

Sequence Map

Chr16:4529181-4537220 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 16, 2.46 cM, cytoband A1
Mapping Data

4 experiments

SNPs within 2kb

266 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1915074	protein coding gene	Chr16:4527923-4537220 (-)
129S1/SvImJ	ENSMUSG00200010293	protein coding gene	Chr16:1519803-1529100 (-)
A/J	ENSMUSG00195010778	protein coding gene	Chr16:1065537-1074830 (-)
AKR/J	ENSMUSG00220016979	protein coding gene	Chr16:1371446-1380743 (-)
BALB/cJ	ENSMUSG00180008130	protein coding gene	Chr16:1320752-1330049 (-)
C3H/HeJ	ENSMUSG00175028547	protein coding gene	Chr16:1512029-1521328 (-)
C57BL/6NJ	ENSMUSG00215011107	protein coding gene	Chr16:1193285-1202584 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0020407	protein coding gene	Chr16:979340-990212 (-)
CAST/EiJ	ENSTCUG00005027896	protein coding gene	Chr16:1398672-1407960 (-)
CBA/J	ENSMUSG00210011879	protein coding gene	Chr16:1529365-1538662 (-)
DBA/2J	ENSMUSG00185009582	protein coding gene	Chr16:1474524-1483821 (-)
FVB/NJ	ENSMUSG00205009476	protein coding gene	Chr16:1396111-1405406 (-)
JF1/MsJ	ENSUMUG00000035186	protein coding gene	Chr16:1506792-1517578 (-)
LP/J	ENSMUSG00230011669	protein coding gene	Chr16:4015556-4024853 (-)
NOD/ShiLtJ	ENSMUSG00190020848	protein coding gene	Chr16:1549940-1559232 (-)
NZO/HlLtJ	ENSMUSG00225022848	protein coding gene	Chr16:7257881-7267178 (-)
PWK/PhJ	ENSLUMG00010016325	protein coding gene	Chr16:1373749-1384551 (-)
SPRET/EiJ	ENSMSPG00010016205	protein coding gene	Chr16:1334338-1345095 (-)
WSB/EiJ	ENSIUOG00005016154	protein coding gene	Chr16:1509712-1519010 (-)

Human Ortholog

NMRAL1, NmrA like redox sensor 1

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

NMRAL1, NmrA like redox sensor 1
Synonyms

HSCARG, SDR48A1
Links

HGNC:24987

NCBI Gene ID: 57407

UniProt: Q9HBL8
Chr Location

16p13.3; chr16:4461684-4495763 (-) GRCh38

MGI Vertebrate Homology

Nmral1 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: NMRAL1
Gene Tree

Nmral1

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Phenotype Summary

5 phenotypes from 1 allele in 2 genetic backgrounds
3 phenotypes from multigenic genotypes
11 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

8
Endonuclease-mediated

2
Gene trapped

1
Targeted

5
Incidental Mutations

APF
Find Mice (IMSR)

24 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

6
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

769
Tissues

41
cDNA Data

10
Literature Summary

4

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase nmral1

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All Sequences

51
RefSeq

8
UniProt

3
CCDS

CCDS27923.1, CCDS70678.1, CCDS70679.1, CCDS70680.1

Ensembl

ENSMUSG00000063445 (Evidence)
NCBI Gene

67824

			Length	Strain/Species	Flank
genomic	67824	NCBI Gene Model \| MGI Sequence Detail	8040	C57BL/6J	± kb
transcript	NM_001290762	RefSeq \| MGI Sequence Detail	1269	C57BL/6
polypeptide	Q8K2T1	UniProt \| EBI \| MGI Sequence Detail	309	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000029645 NmrA-like family domain-containing protein 1

(term hierarchy)
InterPro Domains

IPR036291 NAD(P)-binding domain superfamily

IPR008030 NmrA-like domain

IPR051164 NmrA-like oxidoreductase

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All nucleic 11

cDNA 10

Primer pair 1

Microarray probesets 4

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MGI:2146395

Summaries

All 38

Developmental Gene Expression 4

Gene Ontology 3

Phenotypes 11
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Nmral1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr139791	Chr16:4537012-4537028 (-)	200 bp
Tssr139790	Chr16:4536992-4537010 (-)	219 bp
Tssr139789	Chr16:4536942-4536990 (-)	254 bp
Tssr139788	Chr16:4536907-4536918 (-)	307 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/01/2026 MGI 6.24