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Tmed4 Gene Detail
Summary
  • Symbol
    Tmed4
  • Name
    transmembrane p24 trafficking protein 4
  • Synonyms
    1110014L17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915070
    NCBI Gene: 103694
  • Gene Overview
    MyGene.info: TMED4
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:6270714-6274837 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 3.94 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    28 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915070
protein coding gene Chr11:6270369-6274870 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018019
protein coding gene Chr11:3364879-3369384 (-)
A/J MGP_AJ_G0017992
protein coding gene Chr11:3232102-3236611 (-)
AKR/J MGP_AKRJ_G0017956
protein coding gene Chr11:3392830-3397339 (-)
BALB/cJ MGP_BALBcJ_G0017960
protein coding gene Chr11:3233337-3237774 (-)
C3H/HeJ MGP_C3HHeJ_G0017773
protein coding gene Chr11:3268753-3273259 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018412
protein coding gene Chr11:3473126-3477627 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016070
protein coding gene Chr11:3127635-3132077 (-)
CAST/EiJ MGP_CASTEiJ_G0017335
protein coding gene Chr11:3250517-3254997 (-)
CBA/J MGP_CBAJ_G0017748
protein coding gene Chr11:3864064-3871763 (-)
DBA/2J MGP_DBA2J_G0017858
protein coding gene Chr11:3148464-3153239 (-)
FVB/NJ MGP_FVBNJ_G0017850
protein coding gene Chr11:3162229-3169418 (-)
LP/J MGP_LPJ_G0017929
protein coding gene Chr11:3444653-3449162 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017876
protein coding gene Chr11:3429890-3434369 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018452
protein coding gene Chr11:3409139-3413640 (-)
PWK/PhJ MGP_PWKPhJ_G0017115
protein coding gene Chr11:3173809-3178408 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016912
protein coding gene Chr11:3358395-3362940 (-)
WSB/EiJ MGP_WSBEiJ_G0017389
protein coding gene Chr11:3239100-3243634 (-)



Homology
more
  • Human Ortholog
    TMED4, transmembrane p24 trafficking protein 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TMED4, transmembrane p24 trafficking protein 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ERS25, GMP25iso, HNLF, p24a3, p24alpha3
  • Links
    NCBI Gene ID: 222068
    neXtProt AC: NX_Q7Z7H5
    UniProt: Q7Z7H5

  • Chr Location
    7p13; chr7:44577894-44582295 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 5308
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TMED4
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 103694 NCBI Gene Model | MGI Sequence Detail 4124 C57BL/6J ±  kb
transcript NM_134020 RefSeq | MGI Sequence Detail 1645 Not Specified  
polypeptide Q8R1V4 UniProt | EBI | MGI Sequence Detail 227 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 156
    cDNA 156

    Microarray probesets 4
Other
Accession IDs
less
MGI:2144134
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory