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Rmdn3 Gene Detail
Summary
  • Symbol
    Rmdn3
  • Name
    regulator of microtubule dynamics 3
  • Synonyms
    1200015F23Rik, Fam82a2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915059
    NCBI Gene: 67809
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:119137001-119157034 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 59.94 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    130 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915059
protein coding gene Chr2:119136998-119157034 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026332
protein coding gene Chr2:121869955-121890824 (-)
A/J MGP_AJ_G0026293
protein coding gene Chr2:116910286-116930613 (-)
AKR/J MGP_AKRJ_G0026272
protein coding gene Chr2:120180831-120202311 (-)
BALB/cJ MGP_BALBcJ_G0026306
protein coding gene Chr2:117173317-117193837 (-)
C3H/HeJ MGP_C3HHeJ_G0026052
protein coding gene Chr2:120652547-120672828 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026753
protein coding gene Chr2:125872558-125892590 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024133
protein coding gene Chr2:111963868-111986167 (-)
CAST/EiJ MGP_CASTEiJ_G0025514
protein coding gene Chr2:120955875-120976035 (-)
CBA/J MGP_CBAJ_G0026028
protein coding gene Chr2:130303854-130327801 (-)
DBA/2J MGP_DBA2J_G0026167
protein coding gene Chr2:116338313-116358521 (-)
FVB/NJ MGP_FVBNJ_G0026129
protein coding gene Chr2:115156508-115176810 (-)
LP/J MGP_LPJ_G0026268
protein coding gene Chr2:122183156-122204285 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026148
protein coding gene Chr2:134669106-134690837 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026808
protein coding gene Chr2:120305956-120327045 (-)
PWK/PhJ MGP_PWKPhJ_G0025250
protein coding gene Chr2:115892307-115912752 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025049
protein coding gene Chr2:119492875-119512884 (-)
WSB/EiJ MGP_WSBEiJ_G0025583
protein coding gene Chr2:121134314-121155628 (-)



Homology
more
  • Human Ortholog
    RMDN3, regulator of microtubule dynamics 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RMDN3, regulator of microtubule dynamics 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FAM82A2, FAM82C, ptpip51, RMD3, RMD-3
  • Links
    NCBI Gene ID: 55177
    neXtProt AC: NX_Q96TC7
    UniProt: Q96TC7

  • Chr Location
    15q15.1; chr15:40735884-40755336 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 34926
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: RMDN3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Rmdn3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Phenotypic analysis of mice homozygous for a gene trap allele indicates this mutation has no notable phenotype in any parameter tested.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000070730 Ensembl Gene Model | MGI Sequence Detail 20034 C57BL/6J ±  kb
transcript ENSMUST00000094695 Ensembl | MGI Sequence Detail 2249 Not Applicable  
polypeptide ENSMUSP00000092283 Ensembl | MGI Sequence Detail 470 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    Genomic 2
    cDNA 15
    Primer pair 2

    Microarray probesets 6
Other
Accession IDs
less
MGI:2138842
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory