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Snx2
Gene Detail
Symbol

Name
ID
Snx2
sorting nexin 2
MGI:1915054
Synonyms
0610030A03Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 18
28.99 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:53176365-53220860 bp, + strand
From Ensembl annotation of GRCm38

  44496 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2332  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: sorting nexin, Snx1 type
Gene Tree: Snx2

Human
homologs
Human Homolog SNX2, sorting nexin 2
NCBI Gene ID 6643
neXtProt AC  NX_O60749
Human Synonyms  TRG-9
Human Chr (Location)  5q23; chr5:122774996-122834539 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(21) : Gene trapped(18) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutant mice are viable and fertile and do not exhibit any apparent abnormalities.
 
Interactions
Snx2 interacts with 195 markers (Mir1a-1, Mir1a-2, Mir19a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process early endosome to Golgi transport, endocytosis, ...
Component cytoplasm, endosome, ...
Function epidermal growth factor receptor binding, insulin receptor binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (2)    Tissues (2)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 2
cDNA source data(234)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(235) cDNA(234) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000034484 (Evidence)
Entrez Gene67804 (Evidence)
UniGene252171
DFCITC1573531
DoTSDT.536868
NIA Mouse Gene IndexU018730
Consensus CDS ProjectCCDS37821.1
International Mouse Knockout Project StatusSnx2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034484 Ensembl Gene Model | MGI Sequence Detail 44496 C57BL/6J ±  kb
transcript ENSMUST00000037850 Ensembl | MGI Sequence Detail 2013 Not Applicable 
polypeptide ENSMUSP00000039243 Ensembl | MGI Sequence Detail 519 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(4) UniProt(5)
Polymorphisms
SNPs within 2kb(130 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001683 Phox homologous domain
InterPro IPR005329 Sorting nexin, N-terminal
InterPro IPR015404 Vps5 C-terminal
Protein Ontology PR:000015369 sorting nexin-2
References
(Earliest) J:212820 Haft CR, et al., Identification of a family of sorting nexin molecules and characterization of their association with receptors. Mol Cell Biol. 1998 Dec;18(12):7278-87
(Latest) J:199892 Rhee S, et al., Visceral endoderm expression of Yin-Yang1 (YY1) is required for VEGFA maintenance and yolk sac development. PLoS One. 2013;8(3):e58828
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory