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Snx2 Gene Detail
Summary
  • Symbol
    Snx2
  • Name
    sorting nexin 2
  • Synonyms
    0610030A03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915054
    NCBI Gene: 67804
  • Gene Overview
    MyGene.info: SNX2
Location & Maps
more
  • Sequence Map
    Chr18:53176365-53220860 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      44496 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    SNX2, sorting nexin 2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SNX2, sorting nexin 2
    Orthology source: HomoloGene
  • Synonyms
    TRG-9
  • Links
    NCBI Gene ID: 6643
    neXtProt AC: NX_O60749

  • Chr Location
    5q23; chr5:122774996-122834539 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    21 phenotypes from multigenic genotypes
    7 phenotype references
Homozygous mutant mice are viable and fertile and do not exhibit any apparent abnormalities.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034484 Ensembl Gene Model | MGI Sequence Detail 44496 C57BL/6J ±  kb
transcript ENSMUST00000037850 Ensembl | MGI Sequence Detail 2013 Not Applicable  
polypeptide ENSMUSP00000039243 Ensembl | MGI Sequence Detail 519 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    127 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 235
    cDNA 234
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:212820 Haft CR, et al., Identification of a family of sorting nexin molecules and characterization of their association with receptors. Mol Cell Biol. 1998 Dec;18(12):7278-87
  • Latest
    J:199892 Rhee S, et al., Visceral endoderm expression of Yin-Yang1 (YY1) is required for VEGFA maintenance and yolk sac development. PLoS One. 2013;8(3):e58828

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support.
last database update
05/17/2016
MGI 6.03
The Jackson Laboratory