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Snx2
Gene Detail
 Symbol
Name
ID
Snx2
sorting nexin 2
MGI:1915054
Synonyms 0610030A03Rik
Feature Type protein coding gene
Genetic Map
Chromosome 18
28.99 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:53176365-53220860 bp, + strand
From NCBI annotation of GRCm38

  44496 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2332  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: sorting nexin, Snx1 type
Gene Tree: Snx2

Human
homologs
Human Homolog SNX2, sorting nexin 2
NCBI Gene ID 6643
neXtProt AC  NX_O60749
Human Synonyms  TRG-9
Human Chr (Location)  5q23; chr5:122774996-122834539 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(21) : Gene trapped(18) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutant mice are viable and fertile and do not exhibit any apparent abnormalities.
 
Interactions
Snx2 interacts with 195 markers (Mir1a-1, Mir1a-2, Mir19a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process endocytosis, intracellular protein transport, ...
Component cytoplasm, cytoplasmic membrane-bounded vesicle, ...
Function epidermal growth factor receptor binding, insulin receptor binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (2)    Tissues (2)    Images (1)
Theiler Stages: 13
Assay TypeResults
RT-PCR 2
cDNA source data(234)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(235) cDNA(234) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000034484 (Evidence)
Entrez Gene67804 (Evidence)
UniGene252171
DFCITC1573531
DoTSDT.536868
NIA Mouse Gene IndexU018730
Consensus CDS ProjectCCDS37821.1
International Mouse Knockout Project StatusSnx2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 67804 NCBI Gene Model | MGI Sequence Detail 44496 C57BL/6J ±  kb
transcript NM_026386 RefSeq | MGI Sequence Detail 2013 C57BL/6 
polypeptide Q9CWK8 UniProt | EBI | MGI Sequence Detail 519 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(4) UniProt(3)
Polymorphisms SNPs within 2kb(130 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001683 Phox homologous domain
InterPro IPR005329 Sorting nexin, N-terminal
InterPro IPR015404 Vps5 C-terminal
Protein Ontology PR:000015369 sorting nexin-2
Graphical View of Protein Domain Structure
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:199892 Rhee S, et al., Visceral endoderm expression of Yin-Yang1 (YY1) is required for VEGFA maintenance and yolk sac development. PLoS One. 2013;8(3):e58828
All references(37)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory