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Ahctf1 Gene Detail
Summary
  • Symbol
    Ahctf1
  • Name
    AT hook containing transcription factor 1
  • Synonyms
    6230412P20Rik, Elys
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915033
    NCBI Gene: 226747
  • Gene Overview
    MyGene.info: AHCTF1
Location & Maps
more
  • Sequence Map
    Chr1:179744894-179803680 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      58787 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 83.62 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    AHCTF1, AT-hook containing transcription factor 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    AHCTF1, AT-hook containing transcription factor 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ELYS, MST108, MSTP108, TMBS62
  • Links
    NCBI Gene ID: 25909
    neXtProt AC: NX_Q8WYP5

  • Chr Location
    1q44; chr1:246839098-246931978 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    44
  • Chemically induced (other)
    2
  • Gene trapped
    39
  • Targeted
    3
  • Genomic Mutations
    2 involving Ahctf1
  • Incidental Mutations
Homozygous null mice die between E3.5 and E5.5. The inner cell mass cells exhibit impaired proliferation and apoptosis when grown in culture.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033771 VEGA Gene Model | MGI Sequence Detail 58787 C57BL/6J ±  kb
transcript OTTMUST00000085085 VEGA | MGI Sequence Detail 8506 Not Applicable  
polypeptide OTTMUSP00000045923 VEGA | MGI Sequence Detail 2243 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    324 from dbSNP Build 142
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000003853 AT-hook-containing transcription factor 1
  • PDB
  • InterPro Domains
    IPR032040 ELYS, beta-propeller domain
    IPR025151 ELYS-like domain
Molecular
Reagents
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  • All nucleic 296
    cDNA 295
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2138514
References
more
  • Summaries
    All 41
    Developmental Gene Expression 8
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory