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Ilf2
Gene Detail
 Symbol
Name
ID
Ilf2
interleukin enhancer binding factor 2
MGI:1915031
Synonyms 6230405A16Rik, TEG-267, Tex261, Tex267
Feature Type protein coding gene
Genetic Map
Chromosome 3
39.23 cM, cytoband F2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:90476201-90488379 bp, + strand
From NCBI annotation of GRCm38

  12179 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:26894  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: interleukin enhancer-binding factor 2
Gene Tree: Ilf2

Human
homologs
Human Homolog ILF2, interleukin enhancer binding factor 2
NCBI Gene ID 3608
neXtProt AC  NX_Q12905
Human Synonyms  NF45, PRO3063
Human Chr (Location)  1q21.3; chr1:153661788-153671028 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(27) : Gene trapped(24) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit embryonic lethality.
 
Interactions
Ilf2 interacts with 123 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process immune response, positive regulation of transcription, DNA-templated, ...
Component cytoplasm, membrane, ...
Function ATP binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (88)    Tissues (15)    Images (23)
Theiler Stages: 5, 23
Assay TypeResults
RNA in situ 88
cDNA source data(15)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) cDNA(17)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000001016 (Evidence)
Entrez Gene67781 (Evidence)
DFCITC1574452, TC1683999, TC1709464
NIA Mouse Gene IndexU003494
PDB4ATB, 4AT7, 4AT8, 4AT9
Consensus CDS ProjectCCDS17530.1
International Mouse Knockout Project StatusIlf2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 67781 NCBI Gene Model | MGI Sequence Detail 12179 C57BL/6J ±  kb
transcript NM_026374 RefSeq | MGI Sequence Detail 1973 C57BL/6 
polypeptide Q9CXY6 UniProt | EBI | MGI Sequence Detail 390 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(78 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006116 2-5-oligoadenylate synthetase, N-terminal
InterPro IPR006561 DZF
Protein Ontology PR:000009007 interleukin enhancer-binding factor 2
Graphical View of Protein Domain Structure
References (Earliest) J:35463 Lopez-Fernandez LA, et al., Characterization of genes expressed early in mouse spermatogenesis, isolated from a subtractive cDNA library. Mamm Genome. 1996 Sep;7(9):698-700
(Latest) J:199667 Wolkowicz UM, et al., NF45 dimerizes with NF90, Zfr and SPNR via a conserved domain that has a nucleotidyltransferase fold. Nucleic Acids Res. 2012 Oct;40(18):9356-68
All references(40)
Other
accession IDs
MGI:1096576

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory