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Ilf2
Gene Detail
Symbol

Name
ID
Ilf2
interleukin enhancer binding factor 2
MGI:1915031
Synonyms
6230405A16Rik, TEG-267, Tex261, Tex267
Feature Type
protein coding gene
Genetic Map
Chromosome 3
39.23 cM, cytoband F2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:90476126-90488379 bp, + strand
From VEGA annotation of GRCm38

  12254 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:26894  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: ILF2
Protein SuperFamily: interleukin enhancer-binding factor 2
Gene Tree: Ilf2

Human
homologs
ILF2, interleukin enhancer binding factor 2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 3608
neXtProt AC: NX_Q12905

Human Synonyms: NF45, PRO3063

Human Chr (Location): 1q21.3; chr1:153661788-153671028 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(27) : Gene trapped(24) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit embryonic lethality.
 
Interactions
Ilf2 interacts with 122 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (19 annotations)
Process immune response, positive regulation of transcription, DNA-templated, ...
Component cytoplasm, membrane, ...
Function ATP binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (88)    Tissues (15)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 88
cDNA source data(15)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ilf2    NEW 
Molecular
reagents
All nucleic(17) cDNA(17)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000052750 (Evidence)
Ensembl Gene Model ENSMUSG00000001016 (Evidence)
Entrez Gene 67781 (Evidence)
DFCI TC1574452, TC1683999, TC1709464
NIA Mouse Gene Index U003494
PDB 4AT7, 4AT8, 4AT9, 4ATB
Consensus CDS Project CCDS17530.1
International Mouse Phenotyping Consortium Status Ilf2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000052750 VEGA Gene Model | MGI Sequence Detail 12254 C57BL/6J ±  kb
transcript OTTMUST00000132072 VEGA | MGI Sequence Detail 2027 Not Applicable 
polypeptide OTTMUSP00000070478 VEGA | MGI Sequence Detail 390 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(78 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006116 2-5-oligoadenylate synthetase, N-terminal
InterPro IPR006561 DZF domain
Protein Ontology PR:000009007 interleukin enhancer-binding factor 2
References
(Earliest) J:35463 Lopez-Fernandez LA, et al., Characterization of genes expressed early in mouse spermatogenesis, isolated from a subtractive cDNA library. Mamm Genome. 1996 Sep;7(9):698-700
(Latest) J:199667 Wolkowicz UM, et al., NF45 dimerizes with NF90, Zfr and SPNR via a conserved domain that has a nucleotidyltransferase fold. Nucleic Acids Res. 2012 Oct;40(18):9356-68
All references(39)
Other
accession IDs
MGI:1096576

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory