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Ilf2 Gene Detail
Summary
  • Symbol
    Ilf2
  • Name
    interleukin enhancer binding factor 2
  • Synonyms
    6230405A16Rik, TEG-267, Tex261, Tex267
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915031
    NCBI Gene: 67781
  • Gene Overview
    MyGene.info: ILF2
Location & Maps
more
  • Sequence Map
    Chr3:90476126-90488379 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12254 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 39.23 cM, cytoband F2
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ILF2, interleukin enhancer binding factor 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ILF2, interleukin enhancer binding factor 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    NF45, PRO3063
  • Links
    NCBI Gene ID: 3608
    neXtProt AC: NX_Q12905

  • Chr Location
    1q21.3; chr1:153661788-153671028 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    29
  • Chemically induced (other)
    1
  • Gene trapped
    24
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Ilf2
  • Incidental Mutations
Mice homozygous for a knock-out allele exhibit embryonic lethality.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000052750 VEGA Gene Model | MGI Sequence Detail 12254 C57BL/6J ±  kb
transcript OTTMUST00000132072 VEGA | MGI Sequence Detail 2027 Not Applicable  
polypeptide OTTMUSP00000070478 VEGA | MGI Sequence Detail 390 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    78 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 18

    Microarray probesets 5
Other
Accession IDs
less
MGI:1096576
References
more
  • Summaries
    All 37
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:35463 Lopez-Fernandez LA, et al., Characterization of genes expressed early in mouse spermatogenesis, isolated from a subtractive cDNA library. Mamm Genome. 1996 Sep;7(9):698-700
  • Latest
    J:199667 Wolkowicz UM, et al., NF45 dimerizes with NF90, Zfr and SPNR via a conserved domain that has a nucleotidyltransferase fold. Nucleic Acids Res. 2012 Oct;40(18):9356-68

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory