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Arpc5 Gene Detail
Summary
  • Symbol
    Arpc5
  • Name
    actin related protein 2/3 complex, subunit 5
  • Synonyms
    5830443F10Rik, p16-Arc
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915021
    NCBI Gene: 67771
  • Gene Overview
    MyGene.info: ARPC5
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:152766542-152775580 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 65.02 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    130 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915021
protein coding gene Chr1:152766542-152775597 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016590
protein coding gene Chr1:157536274-157546830 (+)
A/J MGP_AJ_G0016572
protein coding gene Chr1:151193009-151202062 (+)
AKR/J MGP_AKRJ_G0016537
protein coding gene Chr1:155854552-155864820 (+)
BALB/cJ MGP_BALBcJ_G0016532
protein coding gene Chr1:151765814-151775035 (+)
C3H/HeJ MGP_C3HHeJ_G0016357
protein coding gene Chr1:155971648-155980734 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016993
protein coding gene Chr1:162989879-162999752 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014702
protein coding gene Chr1:143511484-143521105 (+)
CAST/EiJ MGP_CASTEiJ_G0015936
protein coding gene Chr1:155474838-155484032 (+)
CBA/J MGP_CBAJ_G0016331
protein coding gene Chr1:168720937-168732952 (+)
DBA/2J MGP_DBA2J_G0016437
protein coding gene Chr1:150208206-150217279 (+)
FVB/NJ MGP_FVBNJ_G0016435
protein coding gene Chr1:148694759-148703830 (+)
LP/J MGP_LPJ_G0016508
protein coding gene Chr1:158649233-158660559 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016461
protein coding gene Chr1:176370687-176380873 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017029
protein coding gene Chr1:155641600-155651084 (+)
PWK/PhJ MGP_PWKPhJ_G0015722
protein coding gene Chr1:149217208-149231325 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015509
protein coding gene Chr1:154449125-154458113 (+)
WSB/EiJ MGP_WSBEiJ_G0015999
protein coding gene Chr1:155705686-155715366 (+)



Homology
more
  • Human Ortholog
    ARPC5, actin related protein 2/3 complex subunit 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ARPC5, actin related protein 2/3 complex subunit 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARC16, dJ127C7.3, p16-Arc
  • Links
    NCBI Gene ID: 10092
    neXtProt AC: NX_O15511
    UniProt: O15511

  • Chr Location
    1q25.3; chr1:183626193-183635941 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 67771 NCBI Gene Model | MGI Sequence Detail 9039 C57BL/6J ±  kb
transcript NM_026369 RefSeq | MGI Sequence Detail 1897 C57BL/6  
polypeptide Q9CPW4 UniProt | EBI | MGI Sequence Detail 151 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000004313 actin-related protein 2/3 complex subunit 5
  • InterPro Domains
    IPR006789 Actin-related protein 2/3 complex subunit 5
    IPR036743 Actin-related protein 2/3 complex subunit 5 superfamily
Molecular
Reagents
less
  • All nucleic 395
    cDNA 395

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:183553 Chang YF, et al., Interaction between microRNAs and actin-associated protein Arpc5 regulates translational suppression during male germ cell differentiation. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5750-5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory