About   Help   FAQ
Gpatch2 Gene Detail
Summary
  • Symbol
    Gpatch2
  • Name
    G patch domain containing 2
  • Synonyms
    5830433G22Rik, 5830436K05Rik, Gpatc2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915019
    NCBI Gene: 67769
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:186947705-187083901 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 90.59 cM, cytoband H5
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    844 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915019
protein coding gene Chr1:186946855-187103839 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016923
protein coding gene Chr1:194018754-194164689 (+)
A/J MGP_AJ_G0016902
protein coding gene Chr1:186082574-186221070 (+)
AKR/J MGP_AKRJ_G0016867
protein coding gene Chr1:191558480-191699506 (+)
BALB/cJ MGP_BALBcJ_G0016860
protein coding gene Chr1:186755888-186891733 (+)
C3H/HeJ MGP_C3HHeJ_G0016684
protein coding gene Chr1:192426998-192572186 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017323
protein coding gene Chr1:200218425-200365102 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015030
protein coding gene Chr1:177059250-177205715 (+)
CAST/EiJ MGP_CASTEiJ_G0016267
protein coding gene Chr1:191935453-192079053 (+)
CBA/J MGP_CBAJ_G0016658
protein coding gene Chr1:207674470-207831208 (+)
DBA/2J MGP_DBA2J_G0016764
protein coding gene Chr1:184846567-184982169 (+)
FVB/NJ MGP_FVBNJ_G0016760
protein coding gene Chr1:182922780-183060291 (+)
LP/J MGP_LPJ_G0016839
protein coding gene Chr1:195192203-195337222 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016792
protein coding gene Chr1:214492570-214642206 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017360
protein coding gene Chr1:191465188-191604167 (+)
PWK/PhJ MGP_PWKPhJ_G0016054
protein coding gene Chr1:184063120-184199776 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015830
protein coding gene Chr1:190423777-190559764 (+)
WSB/EiJ MGP_WSBEiJ_G0016329
protein coding gene Chr1:191645692-191788595 (+)



Homology
more
  • Human Ortholog
    GPATCH2, G-patch domain containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GPATCH2, G-patch domain containing 2
  • Synonyms
    CT110, GPATC2, Pfa1, PPP1R30
  • Links
    NCBI Gene ID: 55105
    neXtProt AC: NX_Q9NW75
    UniProt: Q9NW75

  • Chr Location
    1q41; chr1:217426992-217631090 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele display a small reduction in the frequency of B cells in the blood but no changes in TNF-mediated immune responses.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039210 Ensembl Gene Model | MGI Sequence Detail 136197 C57BL/6J ±  kb
transcript ENSMUST00000065573 Ensembl | MGI Sequence Detail 4547 Not Applicable  
polypeptide ENSMUSP00000065009 Ensembl | MGI Sequence Detail 527 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    cDNA 23

    Microarray probesets 10
Other
Accession IDs
less
MGI:1923285, MGI:2138233, MGI:2138241, MGI:2138559, MGI:2138591
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:336774 Dalseno D, et al., Deletion of Gpatch2 does not alter Tnf expression in mice. Cell Death Dis. 2023 Mar 27;14(3):214

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory