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Prpsap1
Gene Detail
 Symbol
Name
ID
Prpsap1
phosphoribosyl pyrophosphate synthetase-associated protein 1
MGI:1915013
Synonyms 5730409F23Rik, PAP39
Feature Type protein coding gene
Genetic Map
Chromosome 11
81.34 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:116470845-116494202 bp, - strand
From VEGA annotation of GRCm38

  23358 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55687  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: ribose-phosphate pyrophosphokinase catalytic chain
Gene Tree: Prpsap1

Human
homologs
Human Homolog PRPSAP1, phosphoribosyl pyrophosphate synthetase-associated protein 1
NCBI Gene ID 5635
neXtProt AC  NX_Q14558
Human Synonyms  PAP39
Human Chr (Location)  17q24-q25; chr17:76310787-76354149 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(25) : Gene trapped(24) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Prpsap1 interacts with 80 markers (Mir17, Mir20a, Mir20b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process negative regulation of kinase activity, nucleotide biosynthetic process
Component protein complex, ribose phosphate diphosphokinase complex
Function enzyme regulator activity, kinase binding, ...
External Resources: FuncBase
Expression
cDNA source data(118)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(118) cDNA(118)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000003898 (Evidence)
Ensembl Gene ModelENSMUSG00000015869 (Evidence)
Entrez Gene67763 (Evidence)
UniGene25125
DFCITC1574926, TC1595785, TC1762330, TC1766749
DoTSDT.110536531, DT.40158758, DT.94365270, DT.94365283, DT.97406892
NIA Mouse Gene IndexU033653
Consensus CDS ProjectCCDS48985.1
International Mouse Knockout Project StatusPrpsap1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003898 VEGA Gene Model | MGI Sequence Detail 23358 C57BL/6J ±  kb
transcript OTTMUST00000008617 VEGA | MGI Sequence Detail 1841 Not Applicable 
polypeptide OTTMUSP00000004197 VEGA | MGI Sequence Detail 385 Not Applicable 

For the selected sequences
All sequences(73) RefSeq(6) UniProt(5)
Polymorphisms SNPs within 2kb(129 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005946 Ribose-phosphate diphosphokinase
Protein Ontology PR:000013294 phosphoribosyl pyrophosphate synthase-associated protein 1
References (Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory