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Prpsap1 Gene Detail
Summary
  • Symbol
    Prpsap1
  • Name
    phosphoribosyl pyrophosphate synthetase-associated protein 1
  • Synonyms
    5730409F23Rik, PAP39
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915013
    NCBI Gene: 67763
  • Gene Overview
    MyGene.info: PRPSAP1
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:116470845-116494202 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 81.34 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    128 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915013
protein coding gene Chr11:116470816-116494651 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019429
protein coding gene Chr11:120586844-120617591 (-)
A/J MGP_AJ_G0019397
protein coding gene Chr11:115314088-115341048 (-)
AKR/J MGP_AKRJ_G0019368
protein coding gene Chr11:118752220-118778197 (-)
BALB/cJ MGP_BALBcJ_G0019372
protein coding gene Chr11:115720255-115744416 (-)
C3H/HeJ MGP_C3HHeJ_G0019178
protein coding gene Chr11:119108744-119133234 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019821
protein coding gene Chr11:124279658-124304133 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017445
protein coding gene Chr11:112320818-112347414 (-)
CAST/EiJ MGP_CASTEiJ_G0018733
protein coding gene Chr11:120473596-120504936 (-)
CBA/J MGP_CBAJ_G0019149
protein coding gene Chr11:129197819-129223574 (-)
DBA/2J MGP_DBA2J_G0019261
protein coding gene Chr11:114748067-114772285 (-)
FVB/NJ MGP_FVBNJ_G0019253
protein coding gene Chr11:114254475-114277590 (-)
LP/J MGP_LPJ_G0019331
protein coding gene Chr11:120975265-121003456 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019286
protein coding gene Chr11:128244803-128272310 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019860
protein coding gene Chr11:119407961-119438874 (-)
PWK/PhJ MGP_PWKPhJ_G0018497
protein coding gene Chr11:116069665-116094240 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018290
protein coding gene Chr11:119161756-119189140 (-)
WSB/EiJ MGP_WSBEiJ_G0018785
protein coding gene Chr11:119377618-119405644 (-)



Homology
more
  • Human Ortholog
    PRPSAP1, phosphoribosyl pyrophosphate synthetase associated protein 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PRPSAP1, phosphoribosyl pyrophosphate synthetase associated protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PAP39
  • Links
    NCBI Gene ID: 5635
    neXtProt AC: NX_Q14558
    UniProt: Q14558

  • Chr Location
    17q25.1; chr17:76310787-76354149 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000015869 Ensembl Gene Model | MGI Sequence Detail 23358 C57BL/6J ±  kb
transcript ENSMUST00000106391 Ensembl | MGI Sequence Detail 1841 Not Applicable  
polypeptide ENSMUSP00000101999 Ensembl | MGI Sequence Detail 385 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR000836 Phosphoribosyltransferase domain
    IPR029057 Phosphoribosyltransferase-like
    IPR005946 Ribose-phosphate pyrophosphokinase
    IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain
Molecular
Reagents
less
  • All nucleic 119
    Genomic 1
    cDNA 118

    Microarray probesets 4
References
more
  • Summaries
    All 32
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory