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Saxo4 Gene Detail
Summary
  • Symbol
    Saxo4
  • Name
    stabilizer of axonemal microtubules 4
  • Synonyms
    4930579J09Rik, IIIG9, IIIG9L, IIIG9S, Ppp1r32
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915002
    NCBI Gene: 67752
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:10451599-10460292 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 6.60 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    65 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915002
 protein coding gene Chr19:10451599-10463826 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024845
 protein coding gene Chr19:7815121-7823761 (-)
A/J MGP_AJ_G0024813
 protein coding gene Chr19:7282744-7291386 (-)
AKR/J MGP_AKRJ_G0024788
 protein coding gene Chr19:7571882-7580524 (-)
BALB/cJ MGP_BALBcJ_G0024813
 protein coding gene Chr19:7327279-7335921 (-)
C3H/HeJ MGP_C3HHeJ_G0024579
 protein coding gene Chr19:7459588-7468230 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025261
 protein coding gene Chr19:8167583-8176223 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022688
 protein coding gene Chr19:7699890-7707990 (-)
CAST/EiJ MGP_CASTEiJ_G0024052
 protein coding gene Chr19:7114033-7122690 (-)
CBA/J MGP_CBAJ_G0024553
 protein coding gene Chr19:8213898-8222011 (-)
DBA/2J MGP_DBA2J_G0024680
 protein coding gene Chr19:7294725-7303367 (-)
FVB/NJ MGP_FVBNJ_G0024647
 protein coding gene Chr19:7337408-7345524 (-)
LP/J MGP_LPJ_G0024767
 protein coding gene Chr19:7783779-7791891 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024674
 protein coding gene Chr19:8110700-8119342 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025309
 protein coding gene Chr19:7588271-7596384 (-)
PWK/PhJ MGP_PWKPhJ_G0023797
 protein coding gene Chr19:6736784-6745543 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023602
 protein coding gene Chr19:6770030-6778462 (-)
WSB/EiJ MGP_WSBEiJ_G0024114
 protein coding gene Chr19:7471678-7480330 (-)



Homology
more
  • Human Ortholog
    SAXO4, stabilizer of axonemal microtubules 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SAXO4, stabilizer of axonemal microtubules 4
  • Synonyms
    C11orf66, IIIG9, PPP1R32
  • Links
    NCBI Gene ID: 220004
    neXtProt AC: NX_Q7Z5V6
    UniProt: Q7Z5V6

  • Chr Location
    11q12.2; chr11:61481120-61490931 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    719
  • Tissues
    7
  • cDNA Data
    12
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035179 Ensembl Gene Model | MGI Sequence Detail 8694 C57BL/6J ±  kb
transcript ENSMUST00000237522 Ensembl | MGI Sequence Detail 1515 Not Applicable  
polypeptide ENSMUSP00000158578 Ensembl | MGI Sequence Detail 427 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 3
Other
Accession IDs
less
MGI:2147640
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:338030 Zhou L, et al., Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility. Cell. 2023 Jun 22;186(13):2897-2910.e19
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory