About   Help   FAQ
Samsn1
Gene Detail
 Symbol
Name
ID
Samsn1
SAM domain, SH3 domain and nuclear localization signals, 1
MGI:1914992
Synonyms 4930571B16Rik, Hacs1
Feature Type protein coding gene
Genetic Map
Chromosome 16
43.36 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr16:75858793-76022270 bp, - strand
From VEGA annotation of GRCm38

  163478 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11148  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Samsn1

Human
homologs
Human Homolog SAMSN1, SAM domain, SH3 domain and nuclear localization signals 1
NCBI Gene ID 64092
neXtProt AC  NX_Q9NSI8
Human Synonyms  HACS1, NASH1, SASH2, SH3D6B, SLy2
Human Chr (Location)  21q11; chr21:14485228-14583402 (-)  GRCh38
Alleles
and
phenotypes
All alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit enhanced adaptive immunity.
 
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process negative regulation of adaptive immune response, negative regulation of B cell activation, ...
Component cell projection, cytoplasm, ...
Function phosphotyrosine binding, poly(A) RNA binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (83)    Tissues (82)    Images (4)
Theiler Stages: 13, 15, 17, 20, 22, 23, 26, 28
Assay TypeResults
RNA in situ 65
RT-PCR 18
cDNA source data(64)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(68) cDNA(66) Primer pair(2)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000023564 (Evidence)
Ensembl Gene ModelENSMUSG00000022876 (Evidence)
Entrez Gene67742 (Evidence)
UniGene131406
DFCITC1593403, TC1686322, TC1755926
DoTSDT.490667
PDB1V38
Consensus CDS ProjectCCDS37378.1
International Mouse Knockout Project StatusSamsn1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023564 VEGA Gene Model | MGI Sequence Detail 163478 C57BL/6J ±  kb
transcript OTTMUST00000057474 VEGA | MGI Sequence Detail 2518 Not Applicable 
polypeptide OTTMUSP00000027726 VEGA | MGI Sequence Detail 501 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(1111 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR021090 SAM/SH3 domain-containing
InterPro IPR001452 Src homology-3 domain
InterPro IPR001660 Sterile alpha motif domain
InterPro IPR013761 Sterile alpha motif/pointed domain
InterPro IPR011510 Sterile alpha motif, type 2
InterPro IPR011511 Variant SH3
Protein Ontology PR:000029745 SAM domain-containing protein SAMSN-1
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory