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Samsn1
Gene Detail
Symbol

Name
ID
Samsn1
SAM domain, SH3 domain and nuclear localization signals, 1
MGI:1914992
Synonyms
4930571B16Rik, Hacs1
Feature Type
protein coding gene
Genetic Map
Chromosome 16
43.36 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr16:75858793-76022270 bp, - strand
From VEGA annotation of GRCm38

  163478 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11148  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SAMSN1
Gene Tree: Samsn1

Human
homologs
SAMSN1, SAM domain, SH3 domain and nuclear localization signals 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 64092
neXtProt AC: NX_Q9NSI8

Human Synonyms: HACS1, NASH1, SASH2, SH3D6B, SLy2

Human Chr (Location): 21q11; chr21:14485228-14583402 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Targeted(4)
Genomic Mutations involving Samsn1 (3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit enhanced adaptive immunity.
 
Phenotype Images(2)
Interactions
Samsn1 interacts with 160 markers (Mir1b, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (83)    Tissues (83)    Images (4)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 65
RT-PCR 18
cDNA source data(64)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase samsn1 ; ZFIN samsn1a, samsn1b    NEW 
Molecular
reagents
All nucleic(68) cDNA(66) Primer pair(2)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000023564 (Evidence)
Ensembl Gene Model ENSMUSG00000022876 (Evidence)
Entrez Gene 67742 (Evidence)
UniGene 131406
DFCI TC1686322, TC1593403, TC1755926
DoTS DT.490667
PDB 1V38
Consensus CDS Project CCDS37378.1
International Mouse Phenotyping Consortium Status Samsn1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023564 VEGA Gene Model | MGI Sequence Detail 163478 C57BL/6J ±  kb
transcript OTTMUST00000057474 VEGA | MGI Sequence Detail 2518 Not Applicable 
polypeptide OTTMUSP00000027726 VEGA | MGI Sequence Detail 501 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(1111 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR021090 SAM/SH3 domain-containing
InterPro IPR001452 Src homology-3 domain
InterPro IPR001660 Sterile alpha motif domain
InterPro IPR013761 Sterile alpha motif/pointed domain
InterPro IPR011510 Sterile alpha motif, type 2
InterPro IPR011511 Variant SH3
Protein Ontology PR:000029745 SAM domain-containing protein SAMSN-1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory