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Slc25a37
Gene Detail
Symbol

Name
ID
Slc25a37
solute carrier family 25, member 37
MGI:1914962
Synonyms
1700020E22Rik, 4930513O14Rik, 4930526G11Rik, C330015G08Rik, Frascati, Mfrn, Mfrn1, mitoferrin, Mscp
Feature Type
protein coding gene
Genetic Map
Chromosome 14
36.03 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr14:69241848-69285112 bp, - strand
From VEGA annotation of GRCm38

  43265 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:74739  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SLC25A37
Gene Tree: Slc25a37

Human
homologs
SLC25A37, solute carrier family 25 (mitochondrial iron transporter), member 37
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 51312
neXtProt AC: NX_Q9NYZ2

Human Synonyms: HT015, MFRN, MFRN1, MSC, MSCP, PRO1278, PRO1584, PRO2217

Human Chr (Location): 8p21.2; chr8:23528850-23572550 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(2) Targeted(2)
 
Embryos homozygous for a knock-out allele are pale, exhibit no hemoglobinization in the yolk sac and heart, and die during organogenesis.
 
Interactions
Slc25a37 interacts with 294 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (1 annotations)
Component mitochondrion
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (73)    Tissues (26)    Images (36)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 55
Northern blot 14
RT-PCR 4
cDNA source data(12)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase slc25a37 ; ZFIN slc25a37    NEW 
Molecular
reagents
All nucleic(26) cDNA(22) Primer pair(3) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000044494 (Evidence)
Ensembl Gene Model ENSMUSG00000034248 (Evidence)
Entrez Gene 67712 (Evidence)
DFCI TC1583759, TC1603992, TC1614689, TC1584903, TC1589661
DoTS DT.529633, DT.101297587, DT.101387467
NIA Mouse Gene Index U035726
Consensus CDS Project CCDS27238.1
International Mouse Phenotyping Consortium Status Slc25a37
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000044494 VEGA Gene Model | MGI Sequence Detail 43265 C57BL/6J ±  kb
transcript OTTMUST00000117122 VEGA | MGI Sequence Detail 4174 Not Applicable 
polypeptide OTTMUSP00000065509 VEGA | MGI Sequence Detail 338 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(5)
Polymorphisms
SNPs within 2kb(270 from dbSNP Build 137)    SNPs within 2kb including multiple locations(630)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000015031 mitoferrin-1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:204639 Hyde BB, et al., The mitochondrial transporter ABC-me (ABCB10), a downstream target of GATA-1, is essential for erythropoiesis in vivo. Cell Death Differ. 2012 Jul;19(7):1117-26
All references(41)
Other
accession IDs
MGI:1922377, MGI:1925436, MGI:1925952, MGI:2145697

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory