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Aldh3b1 Gene Detail
Summary
  • Symbol
    Aldh3b1
  • Name
    aldehyde dehydrogenase 3 family, member B1
  • Synonyms
    1700001N19Rik, ALDH4, ALDH7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914939
    NCBI Gene: 67689
  • Gene Overview
    MyGene.info: ALDH3B1
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr19:3913493-3929761 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      16269 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 3.63 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ALDH3B1, aldehyde dehydrogenase 3 family member B1
  • Vertebrate Orthologs
    11
  • Human Ortholog
    ALDH3B1, aldehyde dehydrogenase 3 family member B1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ALDH4, ALDH7
  • Links
    NCBI Gene ID: 221
    neXtProt AC: NX_P43353
    UniProt: P43353

  • Chr Location
    11q13.2; chr11:68008547-68029282 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000024885 Ensembl Gene Model | MGI Sequence Detail 16269 C57BL/6J ±  kb
    transcript ENSMUST00000051803 Ensembl | MGI Sequence Detail 1875 Not Applicable  
    polypeptide ENSMUSP00000056276 Ensembl | MGI Sequence Detail 468 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      94 from dbSNP Build 142
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • EC
    • InterPro Domains
      IPR016163 Aldehyde dehydrogenase, C-terminal
      IPR016160 Aldehyde dehydrogenase, cysteine active site
      IPR015590 Aldehyde dehydrogenase domain
      IPR029510 Aldehyde dehydrogenase, glutamic acid active site
      IPR012394 Aldehyde dehydrogenase NAD(P)-dependent
      IPR016162 Aldehyde dehydrogenase, N-terminal
      IPR016161 Aldehyde/histidinol dehydrogenase
    Molecular
    Reagents
    less
    • All nucleic 28
      cDNA 28

      Microarray probesets 3
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 3
      Gene Ontology 5
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:240028 Bulusu V, et al., Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development. Dev Cell. 2017 Feb 27;40(4):331-341.e4

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
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    last database update
    07/10/2018
    MGI 6.12
    The Jackson Laboratory