About   Help   FAQ
Aldh3b1 Gene Detail
Summary
  • Symbol
    Aldh3b1
  • Name
    aldehyde dehydrogenase 3 family, member B1
  • Synonyms
    1700001N19Rik, ALDH4, ALDH7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914939
    NCBI Gene: 67689
  • Gene Overview
    MyGene.info: ALDH3B1
Location & Maps
more
  • Sequence Map
    Chr19:3913493-3929761 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      16269 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 3.63 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ALDH3B1, aldehyde dehydrogenase 3 family member B1
  • Vertebrate Orthologs
    11
  • Human Ortholog
    ALDH3B1, aldehyde dehydrogenase 3 family member B1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ALDH4, ALDH7
  • Links
    NCBI Gene ID: 221
    neXtProt AC: NX_P43353

  • Chr Location
    11q13; chr11:68008547-68029282 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024885 Ensembl Gene Model | MGI Sequence Detail 16269 C57BL/6J ±  kb
transcript ENSMUST00000051803 Ensembl | MGI Sequence Detail 1875 Not Applicable  
polypeptide ENSMUSP00000056276 Ensembl | MGI Sequence Detail 468 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    94 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000031186 aldehyde dehydrogenase family 3 member B1
  • EC
  • InterPro Domains
    IPR016163 Aldehyde dehydrogenase, C-terminal
    IPR016160 Aldehyde dehydrogenase, cysteine active site
    IPR015590 Aldehyde dehydrogenase domain
    IPR029510 Aldehyde dehydrogenase, glutamic acid active site
    IPR012394 Aldehyde dehydrogenase NAD(P)-dependent
    IPR016162 Aldehyde dehydrogenase N-terminal domain
    IPR016161 Aldehyde/histidinol dehydrogenase
Molecular
Reagents
less
  • All nucleic 27
    cDNA 27

    Microarray probesets 3
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:218413 Kitamura T, et al., Mouse aldehyde dehydrogenase ALDH3B2 is localized to lipid droplets via two C-terminal tryptophan residues and lipid modification. Biochem J. 2015 Jan 1;465(1):79-87

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/20/2016
MGI 6.05
The Jackson Laboratory