About   Help   FAQ
Lsm3 Gene Detail
Summary
  • Symbol
    Lsm3
  • Name
    LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
  • Synonyms
    1010001J12Rik, 2610005D18Rik, 6030401D18Rik, SMX4, USS2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914928
    NCBI Gene: 67678
  • Gene Overview
    MyGene.info: LSM3
Location & Maps
more
  • Sequence Map
    Chr6:91515928-91522625 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      6698 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 40.58 cM, cytoband D2
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    LSM3, LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LSM3, LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
    Orthology source: HomoloGene
  • Synonyms
    SMX4, USS2, YLR438C
  • Links
    NCBI Gene ID: 27258
    neXtProt AC: NX_P62310

  • Chr Location
    3p25.1; chr3:14178728-14198369 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    13
  • Gene trapped
    9
  • Spontaneous
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Lsm3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024129 VEGA Gene Model | MGI Sequence Detail 6698 C57BL/6J ±  kb
transcript OTTMUST00000059034 VEGA | MGI Sequence Detail 743 Not Applicable  
polypeptide OTTMUSP00000028680 VEGA | MGI Sequence Detail 102 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    48 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000009961 U6 snRNA-associated Sm-like protein LSm3
  • InterPro Domains
    IPR010920 LSM domain
    IPR001163 LSM domain, eukaryotic/archaea-type
Molecular
Reagents
less
  • All nucleic 83
    cDNA 82
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1917279, MGI:2442209
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/12/2016
MGI 6.04
The Jackson Laboratory