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Cuta Gene Detail
Summary
  • Symbol
    Cuta
  • Name
    cutA divalent cation tolerance homolog
  • Synonyms
    0610039D01Rik, 1810022E02Rik, 1810060C03Rik, 2700094G22Rik, CutA
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914925
    NCBI Gene: 67675
  • Alliance
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:26937973-26939478 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 13.60 cM, cytoband B1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    27 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914925
protein coding gene Chr17:26937972-26939820 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023411
protein coding gene Chr17:26162409-26163914 (-)
A/J MGP_AJ_G0023368
protein coding gene Chr17:25367975-25369480 (-)
AKR/J MGP_AKRJ_G0023334
protein coding gene Chr17:25501566-25503071 (-)
BALB/cJ MGP_BALBcJ_G0023373
protein coding gene Chr17:25609996-25611501 (-)
C3H/HeJ MGP_C3HHeJ_G0023134
protein coding gene Chr17:25876956-25878461 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023816
protein coding gene Chr17:27268294-27269685 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021290
protein coding gene Chr17:22779308-22780797 (-)
CAST/EiJ MGP_CASTEiJ_G0022635
protein coding gene Chr17:25804309-25805804 (-)
CBA/J MGP_CBAJ_G0023108
protein coding gene Chr17:28220260-28221765 (-)
DBA/2J MGP_DBA2J_G0023240
protein coding gene Chr17:24930355-24931860 (-)
FVB/NJ MGP_FVBNJ_G0023209
protein coding gene Chr17:24714451-24715956 (-)
LP/J MGP_LPJ_G0023317
protein coding gene Chr17:26412343-26413848 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023227
protein coding gene Chr17:27735307-27736812 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023857
protein coding gene Chr17:25874834-25876329 (-)
PWK/PhJ MGP_PWKPhJ_G0022385
protein coding gene Chr17:23729197-23730696 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022203
protein coding gene Chr17:23911310-23912806 (-)
WSB/EiJ MGP_WSBEiJ_G0022698
protein coding gene Chr17:25897396-25898900 (-)



Homology
more
  • Human Ortholog
    CUTA, cutA divalent cation tolerance homolog
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CUTA, cutA divalent cation tolerance homolog
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ACHAP, C6orf82
  • Links
    NCBI Gene ID: 51596
    neXtProt AC: NX_O60888
    UniProt: O60888

  • Chr Location
    6p21.32; chr6:33416542-33418288 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024194 Ensembl Gene Model | MGI Sequence Detail 1506 C57BL/6J ±  kb
transcript ENSMUST00000025027 Ensembl | MGI Sequence Detail 639 Not Applicable  
polypeptide ENSMUSP00000025027 Ensembl | MGI Sequence Detail 177 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000006054 protein CutA
  • InterPro Domains
    IPR004323 Divalent ion tolerance protein, CutA
    IPR011322 Nitrogen regulatory PII-like, alpha/beta
    IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal
Molecular
Reagents
less
  • All nucleic 103
    cDNA 103

    Microarray probesets 3
Other
Accession IDs
less
MGI:1916374, MGI:1917082, MGI:1919869, MGI:2146831
References
more
  • Summaries
    All 36
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:221689 Hou P, et al., Role of copper and the copper-related protein CUTA in mediating APP processing and Abeta generation. Neurobiol Aging. 2015 Mar;36(3):1310-5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory