About   Help   FAQ
Rpl38
Gene Detail
 Symbol
Name
ID
Rpl38
ribosomal protein L38
MGI:1914921
Synonyms 0610025G13Rik, Rbt, Ts, Tss
Feature Type protein coding gene
Genetic Map
Chromosome 11
79.82 cM, cytoband G1
Detailed Genetic Map ± 1 cM


Mapping data(15)
Sequence Map
Chr11:114668524-114672331 bp, + strand
From VEGA annotation of GRCm38

  3808 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:87098  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: ribosomal protein L38
Gene Tree: Rpl38

Human
homologs
Human Homolog RPL38, ribosomal protein L38
NCBI Gene ID 6169
neXtProt AC  NX_P63173
Human Synonyms  L38
Human Chr (Location)  17q25.1; chr17:74203656-74209880 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(82) : Chemically induced (ENU)(1) Gene trapped(76) Spontaneous(2) Targeted(3)
 
Mutations in this gene affect growth and tail formation, and result in anterior and posterior homeotic vertebral transformations along the axial skeleton along with other abnormalities depending on genetic background. Homozygotes die in the early embryonic period.
 
Human Diseases Modeled Using Mouse Rpl38 (1)    Alleles Annotated to Human Diseases(1)    Phenotype Images(2)
Interactions
Rpl38 interacts with 1 marker (Mir511)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process 90S preribosome assembly, axial mesoderm development, ...
Component cytosolic large ribosomal subunit, eukaryotic 80S initiation complex, ...
Function structural constituent of ribosome
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (5)    Tissues (1)    Images (5)
Theiler Stages: 23
Assay TypeResults
RNA in situ 5
cDNA source data(10)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(10) cDNA(10)
Microarray probesets(8)
Other database
links
VEGA Gene ModelOTTMUSG00000003385 (Evidence)
Ensembl Gene ModelENSMUSG00000057322 (Evidence)
Entrez Gene67671 (Evidence)
DFCITC1573229, TC1699576
DoTSDT.101328404, DT.101373475, DT.110545072, DT.94379865, DT.99864048
Consensus CDS ProjectCCDS36365.1
International Mouse Knockout Project StatusRpl38
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003385 VEGA Gene Model | MGI Sequence Detail 3808 C57BL/6J ±  kb
transcript OTTMUST00000007095 VEGA | MGI Sequence Detail 371 Not Applicable 
polypeptide OTTMUSP00000003375 VEGA | MGI Sequence Detail 70 Not Applicable 

For the selected sequences
All sequences(59) RefSeq(12) UniProt(2)
Polymorphisms SNPs within 2kb(53 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002675 Ribosomal protein L38e
Protein Ontology PR:000014224 60S ribosomal protein L38
References (Earliest) J:13063 MORGAN WC, A new tail-short mutation in the mouse whose lethal effects are conditioned by the residual genotypes. J Hered. 1950 Aug;41(8):208-15
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(56)
Disease annotation references (1)
Other
accession IDs
MGD-MRK-15255, MGD-MRK-37425, MGI:108385, MGI:1859966, MGI:98840

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/09/2014
MGI 5.19
The Jackson Laboratory