Rpl38
Gene Detail

Symbol Name ID

Rpl38 ribosomal protein L38 MGI:1914921

Synonyms

0610025G13Rik, Rbt, Ts, Tss

Feature Type

protein coding gene

Genetic Map

Chromosome 11

79.82 cM, cytoband G1
Detailed Genetic Map ± 1 cM


Mapping data(15)

Sequence Map

Chr11:114668524-114672331 bp, + strand From VEGA annotation of GRCm38   3808 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:87098  Vertebrate Homology Class
1 human; 1 mouse; 3 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 zebrafish

Protein SuperFamily: ribosomal protein L38
Gene Tree: Rpl38

Human homologs

Human Homolog		RPL38, ribosomal protein L38
NCBI Gene ID		6169
neXtProt AC		NX_P63173
Human Synonyms		L38
Human Chr (Location)		17q25.1; chr17:72199795-72206019 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(83) : Targeted(3) Gene trapped(77) Spontaneous(2) Chemically induced(1)
 

Mutations in this gene affect growth and tail formation, and result in anterior and posterior homeotic vertebral transformations along the axial skeleton along with other abnormalities depending on genetic background. Homozygotes die in the early embryonic period.

 
Human Diseases Modeled Using Mouse Rpl38 (1)    Alleles Annotated to Human Diseases(1)    Phenotype Images(2)

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	90S preribosome assembly, axial mesoderm development, ...
Component	cytosolic large ribosomal subunit, eukaryotic 80S initiation complex, ...
Function	structural constituent of ribosome

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (5)    Tissues (1)    Images (5)
Theiler Stages: 23

Assay Type	Results
RNA in situ	5

cDNA source data(10)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(10) cDNA(10)
Microarray probesets(8)

Other database links

VEGA Gene Model	OTTMUSG00000003385 (Evidence)
Ensembl Gene Model	ENSMUSG00000057322 (Evidence)
Entrez Gene	67671 (Evidence)
DFCI	TC1573229, TC1699576
DoTS	DT.101328404, DT.101373475, DT.110545072, DT.94379865, DT.99864048
Consensus CDS Project	CCDS36365.1
International Mouse Knockout Project Status	Rpl38

Sequences

Length	Strain/Species
genomic	OTTMUSG00000003385	VEGA Gene Model | MGI Sequence Detail	3808	C57BL/6J
transcript	OTTMUST00000007095	VEGA | MGI Sequence Detail	371	Not Applicable
polypeptide	OTTMUSP00000003375	VEGA | MGI Sequence Detail	70	Not Applicable

All sequences(53) RefSeq(6) UniProt(2)

Polymorphisms

SNPs(43 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR002675	Ribosomal protein L38e
Protein Ontology	PR:000014224	60S ribosomal protein L38

References

(Earliest) J:13063 MORGAN WC, A new tail-short mutation in the mouse whose lethal effects are conditioned by the residual genotypes. J Hered. 1950 Aug;41(8):208-15
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(56)

Other accession IDs

MGD-MRK-15255, MGD-MRK-37425, MGI:108385, MGI:1859966, MGI:98840