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Spaca1
Gene Detail
 Symbol
Name
ID
Spaca1
sperm acrosome associated 1
MGI:1914902
Synonyms 1700124L11Rik, 4930540L03Rik
Feature Type protein coding gene
Genetic Map
Chromosome 4
16.63 cM, cytoband A5
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:34024874-34050191 bp, - strand
From VEGA annotation of GRCm38

  25318 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12170  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Spaca1

Human
homologs
Human Homolog SPACA1, sperm acrosome associated 1
NCBI Gene ID 81833
neXtProt AC  NX_Q9HBV2
Human Synonyms  SAMP32
Human Chr (Location)  6q15; chr6:88047789-88066832 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null male mice are infertile and display globozoospermia and asthenozoospermia.
 
Interactions
Spaca1 interacts with 40 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process acrosome assembly, spermatogenesis
Component acrosomal membrane, integral component of membrane, ...
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000008303 (Evidence)
Ensembl Gene ModelENSMUSG00000028264 (Evidence)
Entrez Gene67652 (Evidence)
UniGene55848
DFCITC1586437, TC1593072
DoTSDT.101353589, DT.55150764, DT.55281664
NIA Mouse Gene IndexU024928
Consensus CDS ProjectCCDS18026.1, CCDS71357.1
International Mouse Knockout Project StatusSpaca1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000008303 VEGA Gene Model | MGI Sequence Detail 25318 C57BL/6J ±  kb
transcript OTTMUST00000018897 VEGA | MGI Sequence Detail 1197 Not Applicable 
polypeptide OTTMUSP00000008681 VEGA | MGI Sequence Detail 305 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(4) UniProt(5)
Polymorphisms SNPs within 2kb(90 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000015448 sperm acrosome membrane-associated protein 1
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:187685 Fujihara Y, et al., SPACA1-deficient male mice are infertile with abnormally shaped sperm heads reminiscent of globozoospermia. Development. 2012 Oct;139(19):3583-9
All references(24)
Other
accession IDs
MGI:1923894

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory