4930522H14Rik MGI Mouse Gene Detail - MGI:1914896

Symbol

4930522H14Rik
Name

RIKEN cDNA 4930522H14 gene
Synonyms

1700007J23Rik

Feature Type

protein coding gene
IDs

MGI:1914896
NCBI Gene: 67646
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr4:109362534-109388494 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 4, 51.29 cM, cytoband C7
Mapping Data

2 experiments

SNPs within 2kb

36 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914896	protein coding gene	Chr4:109362529-109388494 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0028572	protein coding gene	Chr4:110281549-110307135 (-)
A/J	MGP_AJ_G0028535	protein coding gene	Chr4:106312250-106337801 (-)
AKR/J	MGP_AKRJ_G0028482	protein coding gene	Chr4:108958609-108989124 (-)
BALB/cJ	MGP_BALBcJ_G0028554	protein coding gene	Chr4:106527170-106553231 (-)
C3H/HeJ	MGP_C3HHeJ_G0028268	protein coding gene	Chr4:109712383-109741773 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0028994	protein coding gene	Chr4:114241819-114268253 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0026285	protein coding gene	Chr4:101609401-101635428 (-)
CAST/EiJ	MGP_CASTEiJ_G0027704	protein coding gene	Chr4:107563555-107590912 (-)
CBA/J	MGP_CBAJ_G0028237	protein coding gene	Chr4:117993480-118039566 (-)
DBA/2J	MGP_DBA2J_G0028385	protein coding gene	Chr4:105933633-105958116 (-)
FVB/NJ	MGP_FVBNJ_G0028353	protein coding gene	Chr4:104810571-104834287 (-)
LP/J	MGP_LPJ_G0028486	protein coding gene	Chr4:110538516-110580723 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0028379	protein coding gene	Chr4:123175699-123203863 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0029030	protein coding gene	Chr4:109201418-109224975 (-)
PWK/PhJ	MGP_PWKPhJ_G0027430	protein coding gene	Chr4:104224636-104253560 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0027254	protein coding gene	Chr4:106588687-106613203 (-)
WSB/EiJ	MGP_WSBEiJ_G0027785	protein coding gene	Chr4:109384838-109412199 (-)

Human Ortholog

C1orf185, chromosome 1 open reading frame 185

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

C1orf185, chromosome 1 open reading frame 185
Links

HGNC:28096

NCBI Gene ID: 284546

neXtProt AC: NX_Q5T7R7

UniProt: Q5T7R7
Chr Location

1p32.3; chr1:51102221-51152282 (+) GRCh38

MGI Vertebrate Homology

4930522H14Rik stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: C1orf185
Gene Tree

4930522H14Rik

less

Phenotype Summary

2 phenotypes from 2 alleles in 2 genetic backgrounds
10 phenotype references

All Mutations and Alleles

8
Chemically induced (other)

2
Endonuclease-mediated

2
Radiation induced

1
Targeted

3
Genomic Mutations

4 involving 4930522H14Rik
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

15 strains or lines available

Mice homozygous for null mutations in this gene are viable and show normal male fertility.

less

All GO Annotations

1
GO References

1

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

7

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

less

All Sequences

35
RefSeq

4
UniProt

1
CCDS

CCDS18465.1, CCDS57290.1

Ensembl

ENSMUSG00000060491 (Evidence)
NCBI Gene

67646

			Length	Strain/Species	Flank
genomic	ENSMUSG00000060491	Ensembl Gene Model \| MGI Sequence Detail	25961	C57BL/6J	± kb
transcript	ENSMUST00000102725	Ensembl \| MGI Sequence Detail	854	Not Applicable
polypeptide	ENSMUSP00000099786	Ensembl \| MGI Sequence Detail	230	Not Applicable

less

UniProt

1 Sequence
Protein Ontology

PR:000059829 uncharacterized protein C1orf185

(term hierarchy)
InterPro Domains

IPR031695 Protein of unknown function DUF4718

less

All nucleic 7

cDNA 7

Microarray probesets 3

less

MGI:1921466

Summaries

All 29

Gene Ontology 1

Phenotypes 10
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:323102 Cazin C, et al., Combined Use of Whole Exome Sequencing and CRISPR/Cas9 to Study the Etiology of Non-Obstructive Azoospermia: Demonstration of the Dispensable Role of the Testis-Specific Genes C1orf185 and CCT6B. Cells. 2021 Dec 30;11(1)

TSS for 4930522H14Rik:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr42772	Chr4:109388423-109388429 (-)	68 bp
Tssr42771	Chr4:109388414-109388417 (-)	78 bp
Tssr42770	Chr4:109388395-109388409 (-)	92 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23