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Armc12 Gene Detail
Summary
  • Symbol
    Armc12
  • Name
    armadillo repeat containing 12
  • Synonyms
    4930511I11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914895
    NCBI Gene: 67645
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:28749835-28757949 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 14.74 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    14 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914895
protein coding gene Chr17:28749780-28758084 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023442
protein coding gene Chr17:27946609-27957841 (+)
A/J MGP_AJ_G0023400
protein coding gene Chr17:27014471-27022673 (+)
AKR/J MGP_AKRJ_G0023365
protein coding gene Chr17:27222761-27232353 (+)
BALB/cJ MGP_BALBcJ_G0023405
protein coding gene Chr17:27285899-27298215 (+)
C3H/HeJ MGP_C3HHeJ_G0023166
protein coding gene Chr17:27609819-27618412 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023847
protein coding gene Chr17:29075202-29088109 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021322
protein coding gene Chr17:24383461-24392193 (+)
CAST/EiJ MGP_CASTEiJ_G0022667
protein coding gene Chr17:27590293-27598613 (+)
CBA/J MGP_CBAJ_G0023140
protein coding gene Chr17:30116238-30132843 (+)
DBA/2J MGP_DBA2J_G0023271
protein coding gene Chr17:26572872-26580873 (+)
FVB/NJ MGP_FVBNJ_G0023241
protein coding gene Chr17:26386782-26409482 (+)
LP/J MGP_LPJ_G0023349
protein coding gene Chr17:28204205-28213779 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023259
protein coding gene Chr17:29534557-29544306 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023889
protein coding gene Chr17:27662678-27670771 (+)
PWK/PhJ MGP_PWKPhJ_G0022417
protein coding gene Chr17:25391548-25400011 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022235
protein coding gene Chr17:25641525-25649133 (+)
WSB/EiJ MGP_WSBEiJ_G0022729
protein coding gene Chr17:27651428-27660978 (+)



Homology
more
  • Human Ortholog
    ARMC12, armadillo repeat containing 12
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARMC12, armadillo repeat containing 12
  • Synonyms
    C6orf81
  • Links
    NCBI Gene ID: 221481
    neXtProt AC: NX_Q5T9G4
    UniProt: Q5T9G4

  • Chr Location
    6p21.31; chr6:35733726-35748913 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotypes from 3 alleles in 2 genetic backgrounds
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit male infertility associated with abnormal sperm flagellum morphology and function.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67645 NCBI Gene Model | MGI Sequence Detail 8115 C57BL/6J ±  kb
    transcript NM_026290 RefSeq | MGI Sequence Detail 1103 C57BL/6  
    polypeptide Q80X86 UniProt | EBI | MGI Sequence Detail 340 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 8

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2147014
    References
    more
    • Summaries
      All 22
      Phenotypes 5
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:302631 Shimada K, et al., ARMC12 regulates spatiotemporal mitochondrial dynamics during spermiogenesis and is required for male fertility. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6)

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.
    last database update
    10/19/2021
    MGI 6.17
    The Jackson Laboratory