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Uchl5 Gene Detail
Summary
  • Symbol
    Uchl5
  • Name
    ubiquitin carboxyl-terminal esterase L5
  • Synonyms
    5830413B11Rik, Uch37
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914848
    NCBI Gene: 56207
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr1:143777272-143807466 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      30195 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 62.54 cM, cytoband F
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    UCHL5, ubiquitin C-terminal hydrolase L5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    UCHL5, ubiquitin C-terminal hydrolase L5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CGI-70, INO80R, UCH37, UCH-L5
  • Links
    NCBI Gene ID: 51377
    neXtProt AC: NX_Q9Y5K5
    UniProt: Q9Y5K5

  • Chr Location
    1q31.2; chr1:193012366-193060140 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 2 alleles in 2 genetic backgrounds
    1 images
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap allele exhibit embryonic lethality associated with abnormal brain development.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000049324 VEGA Gene Model | MGI Sequence Detail 30195 C57BL/6J ±  kb
    transcript OTTMUST00000125747 VEGA | MGI Sequence Detail 1696 Not Applicable  
    polypeptide OTTMUSP00000068082 VEGA | MGI Sequence Detail 329 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      186 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 63
      cDNA 63

      Microarray probesets 7
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 3
      Gene Ontology 7
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:242651 Kim SK, et al., Strain survey and genetic analysis of vasoreactivity in mouse aorta. Physiol Genomics. 2016 Oct 07;:physiolgenomics.00054.2016

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    05/15/2018
    MGI 6.12
    The Jackson Laboratory