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Tctn3 Gene Detail
Summary
  • Symbol
    Tctn3
  • Name
    tectonic family member 3
  • Synonyms
    4930521E07Rik, Tect3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914840
    NCBI Gene: 67590
  • Gene Overview
    MyGene.info: TCTN3
Location & Maps
more
  • Sequence Map
    Chr19:40596446-40612233 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      15788 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    TCTN3, tectonic family member 3
  • Vertebrate Orthologs
    7
  • Human Ortholog
    TCTN3, tectonic family member 3
    Orthology source: HomoloGene
  • Synonyms
    C10orf61, JBTS18, OFD4, TECT3
  • Links
    NCBI Gene ID: 26123
    neXtProt AC: NX_Q6NUS6

  • Chr Location
    10q24.1; chr10:95663396-95694143 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    3 with human TCTN3 associations

Human Disease Mouse Models
       Joubert Syndrome 18; JBTS18   OMIM: 614815
Joubert Syndrome 1; JBTS1   OMIM: 213300
Orofaciodigital Syndrome IV; OFD4   OMIM: 258860
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029015 VEGA Gene Model | MGI Sequence Detail 15788 C57BL/6J ±  kb
transcript OTTMUST00000071986 VEGA | MGI Sequence Detail 2743 Not Applicable  
polypeptide OTTMUSP00000036966 VEGA | MGI Sequence Detail 595 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    126 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000016211 tectonic-3
  • InterPro Domains
    IPR011677 Domain of unknown function DUF1619
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 5
Other
Accession IDs
less
MGI:2147490
References
more
  • Summaries
    All 24
    Developmental Gene Expression 2
    Gene Ontology 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:176174 Garcia-Gonzalo FR, et al., A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition. Nat Genet. 2011 Aug;43(8):776-84

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory