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Tctn3 Gene Detail
Summary
  • Symbol
    Tctn3
  • Name
    tectonic family member 3
  • Synonyms
    4930521E07Rik, Tect3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914840
    NCBI Gene: 67590
  • Gene Overview
    MyGene.info: TCTN3
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:40596446-40612233 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 34.25 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    126 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914840
protein coding gene Chr19:40596446-40612281 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025113
protein coding gene Chr19:39812530-39828286 (-)
A/J MGP_AJ_G0025090
protein coding gene Chr19:37872132-37887909 (-)
AKR/J MGP_AKRJ_G0025058
protein coding gene Chr19:39163668-39179444 (-)
BALB/cJ MGP_BALBcJ_G0025084
protein coding gene Chr19:37963071-37978807 (-)
C3H/HeJ MGP_C3HHeJ_G0024844
protein coding gene Chr19:39306479-39322203 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025528
protein coding gene Chr19:40895155-40910781 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022941
protein coding gene Chr19:37281383-37297183 (-)
CAST/EiJ MGP_CASTEiJ_G0024309
protein coding gene Chr19:38936033-38953137 (-)
CBA/J MGP_CBAJ_G0024824
protein coding gene Chr19:42884779-42903417 (-)
DBA/2J MGP_DBA2J_G0024956
protein coding gene Chr19:37776836-37792664 (-)
FVB/NJ MGP_FVBNJ_G0024917
protein coding gene Chr19:37528396-37544149 (-)
LP/J MGP_LPJ_G0025042
protein coding gene Chr19:39850379-39867838 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024948
protein coding gene Chr19:42580678-42597618 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025585
protein coding gene Chr19:39194310-39209921 (-)
PWK/PhJ MGP_PWKPhJ_G0024059
protein coding gene Chr19:37621059-37637060 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023862
protein coding gene Chr19:37921405-37937184 (-)
WSB/EiJ MGP_WSBEiJ_G0024379
protein coding gene Chr19:39356111-39372283 (-)



Homology
more
  • Human Ortholog
    TCTN3, tectonic family member 3
  • Vertebrate Orthologs
    7
  • Human Ortholog
    TCTN3, tectonic family member 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C10orf61, JBTS18, OFD4, TECT3
  • Links
    NCBI Gene ID: 26123
    neXtProt AC: NX_Q6NUS6
    UniProt: Q6NUS6

  • Chr Location
    10q24.1; chr10:95663396-95694143 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    2 with human TCTN3 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025008 Ensembl Gene Model | MGI Sequence Detail 15788 C57BL/6J ±  kb
transcript ENSMUST00000025981 Ensembl | MGI Sequence Detail 2743 Not Applicable  
polypeptide ENSMUSP00000025981 Ensembl | MGI Sequence Detail 595 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR011677 Domain of unknown function DUF1619
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 5
Other
Accession IDs
less
MGI:2147490
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 1
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:249241 Wang C, et al., Three Tctn proteins are functionally conserved in the regulation of neural tube patterning and Gli3 processing but not ciliogenesis and Hedgehog signaling in the mouse. Dev Biol. 2017 Oct 1;430(1):156-165

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory