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Lrrc18 Gene Detail
Summary
  • Symbol
    Lrrc18
  • Name
    leucine rich repeat containing 18
  • Synonyms
    4930442L21Rik, mtLR1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914830
    NCBI Gene: 67580
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:32991382-33015291 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 19.61 cM, cytoband B
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    203 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914830
protein coding gene Chr14:32991382-33015300 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021154
protein coding gene Chr14:26274458-26298317 (+)
A/J MGP_AJ_G0021102
protein coding gene Chr14:25264610-25288462 (+)
AKR/J MGP_AKRJ_G0021079
protein coding gene Chr14:26412830-26436740 (+)
BALB/cJ MGP_BALBcJ_G0021106
protein coding gene Chr14:25440356-25464208 (+)
C3H/HeJ MGP_C3HHeJ_G0020889
protein coding gene Chr14:26306074-26329968 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021538
protein coding gene Chr14:27299861-27324811 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019100
protein coding gene Chr14:25317659-25341512 (+)
CAST/EiJ MGP_CASTEiJ_G0020414
protein coding gene Chr14:26115565-26140383 (+)
CBA/J MGP_CBAJ_G0020856
protein coding gene Chr14:28323636-28347474 (+)
DBA/2J MGP_DBA2J_G0020978
protein coding gene Chr14:25310885-25335143 (+)
FVB/NJ MGP_FVBNJ_G0020962
protein coding gene Chr14:25253775-25277625 (+)
LP/J MGP_LPJ_G0021047
protein coding gene Chr14:26589423-26615340 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020988
protein coding gene Chr14:27509916-27535428 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021571
protein coding gene Chr14:26220166-26244040 (+)
PWK/PhJ MGP_PWKPhJ_G0020162
protein coding gene Chr14:24774949-24799428 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019986
protein coding gene Chr14:25856127-25879899 (+)
WSB/EiJ MGP_WSBEiJ_G0020469
protein coding gene Chr14:26284981-26311466 (+)



Homology
more
  • Human Ortholog
    LRRC18, leucine rich repeat containing 18
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LRRC18, leucine rich repeat containing 18
    Orthology source: HomoloGene, HGNC
  • Synonyms
    UNQ933, UNQ9338, VKGE9338
  • Links
    NCBI Gene ID: 474354
    neXtProt AC: NX_Q8N456
    UniProt: Q8N456

  • Chr Location
    chr10:48881011-48940126 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 81914
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: LRRC18
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041673 Ensembl Gene Model | MGI Sequence Detail 23910 C57BL/6J ±  kb
transcript ENSMUST00000120951 Ensembl | MGI Sequence Detail 1511 Not Applicable  
polypeptide ENSMUSP00000113965 Ensembl | MGI Sequence Detail 309 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR001611 Leucine-rich repeat
    IPR032675 Leucine-rich repeat domain superfamily
    IPR003591 Leucine-rich repeat, typical subtype
Molecular
Reagents
less
  • All nucleic 56
    cDNA 56

    Microarray probesets 7
References
more
  • Summaries
    All 22
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/19/2019
MGI 6.13
The Jackson Laboratory