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Loxl4
Gene Detail
Symbol

Name
ID
Loxl4
lysyl oxidase-like 4
MGI:1914823
Synonyms
4833426I20Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 19
36.56 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr19:42593982-42612813 bp, - strand
From VEGA annotation of GRCm38

  18832 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12977  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: LOXL4
Gene Tree: Loxl4

Human
homologs
LOXL4, lysyl oxidase-like 4
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 84171
neXtProt AC: NX_Q96JB6

Human Synonyms: LOXC

Human Chr (Location): 10q24; chr10:98247686-98268250 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Loxl4 interacts with 223 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process oxidation-reduction process
Component extracellular exosome, extracellular region, ...
Function aspartate oxidase activity, copper ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (83)    Tissues (10)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 83
cDNA source data(13)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000035803 (Evidence)
Ensembl Gene Model ENSMUSG00000025185 (Evidence)
Entrez Gene 67573 (Evidence)
UniGene 178767
DFCI TC1584211, TC1589638, TC1605221
DoTS DT.101358230, DT.40166256
NIA Mouse Gene Index U039052
EC 1.4.3.-
Consensus CDS Project CCDS29830.1, CCDS50441.1
International Mouse Phenotyping Consortium Status Loxl4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035803 VEGA Gene Model | MGI Sequence Detail 18832 C57BL/6J ±  kb
transcript OTTMUST00000091707 VEGA | MGI Sequence Detail 2617 Not Applicable 
polypeptide OTTMUSP00000050536 VEGA | MGI Sequence Detail 758 Not Applicable 

For the selected sequences
All sequences(49) RefSeq(8) UniProt(7)
Polymorphisms
SNPs within 2kb(277 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001695 Lysyl oxidase
InterPro IPR019828 Lysyl oxidase, conserved site
InterPro IPR001190 SRCR domain
InterPro IPR017448 SRCR-like domain
Protein Ontology PR:000009887 lysyl oxidase homolog 4
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:194542 Ghai R, et al., Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):E643-52
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory