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Mrfap1 Gene Detail
Summary
  • Symbol
    Mrfap1
  • Name
    Morf4 family associated protein 1
  • Synonyms
    9130413I22Rik, PAM14
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914818
    NCBI Gene: 67568
  • Gene Overview
    MyGene.info: MRFAP1
Location & Maps
more
  • Sequence Map
    Chr5:36794867-36796772 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1906 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 19.26 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    MRFAP1, Morf4 family associated protein 1
  • Vertebrate Orthologs
    6
  • Human Ortholog
    MRFAP1, Morf4 family associated protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PAM14, PGR1
  • Links
    NCBI Gene ID: 93621
    neXtProt AC: NX_Q9Y605

  • Chr Location
    4p16.1; chr4:6640091-6642745 (+)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    24 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (ENU)
    1
  • Chemically induced (other)
    2
  • Gene trapped
    1
  • Radiation induced
    5
  • Spontaneous
    1
  • Targeted
    1
  • Genomic Mutations
    9 involving Mrfap1
  • Incidental Mutations
Homozygous null mice are viable, fertile, develop normally, have normal T cell development and function, and produce MEFs with normal growth rates and times to senescence.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024873 VEGA Gene Model | MGI Sequence Detail 1906 C57BL/6J ±  kb
transcript OTTMUST00000061272 VEGA | MGI Sequence Detail 1648 Not Applicable  
polypeptide OTTMUSP00000030015 VEGA | MGI Sequence Detail 125 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    18 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR029254 MORF4 family-associated protein 1
Molecular
Reagents
less
  • All nucleic 17
    cDNA 16
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2141014
References
more
  • Summaries
    All 24
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 3
    Phenotypes 24
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory