Mgat4d MGI Mouse Gene Detail - MGI:1914805

Symbol

Mgat4d
Name

MGAT4 family, member C
Synonyms

4933434I20Rik

Feature Type

protein coding gene
IDs

MGI:1914805
NCBI Gene: 67555
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr8:84075101-84106031 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 8, 39.84 cM, cytoband C3
Mapping Data

2 experiments

SNPs within 2kb

566 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914805	protein coding gene	Chr8:84075100-84108949 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0033830	protein coding gene	Chr8:84150885-84188783 (+)
A/J	MGP_AJ_G0033813	protein coding gene	Chr8:80866130-80903558 (+)
AKR/J	MGP_AKRJ_G0033739	protein coding gene	Chr8:83251203-83285892 (+)
BALB/cJ	MGP_BALBcJ_G0033806	protein coding gene	Chr8:80972245-81007182 (+)
C3H/HeJ	MGP_C3HHeJ_G0033515	protein coding gene	Chr8:83883745-83918929 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0034326	protein coding gene	Chr8:87399458-87434667 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0031267	protein coding gene	Chr8:74703828-74736955 (+)
CAST/EiJ	MGP_CASTEiJ_G0032846	protein coding gene	Chr8:83275226-83313268 (+)
CBA/J	MGP_CBAJ_G0033494	protein coding gene	Chr8:90512668-90560445 (+)
DBA/2J	MGP_DBA2J_G0033647	protein coding gene	Chr8:80508302-80547319 (+)
FVB/NJ	MGP_FVBNJ_G0033592	protein coding gene	Chr8:79434204-79466124 (+)
LP/J	MGP_LPJ_G0033737	protein coding gene	Chr8:84271366-84322099 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0033635	protein coding gene	Chr8:93026907-93071387 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0034343	protein coding gene	Chr8:83255096-83289045 (+)
PWK/PhJ	MGP_PWKPhJ_G0032549	protein coding gene	Chr8:79728965-79766353 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0032387	protein coding gene	Chr8:82053073-82088179 (+)
WSB/EiJ	MGP_WSBEiJ_G0032959	protein coding gene	Chr8:83638593-83677038 (+)

Human Ortholog

MGAT4D, MGAT4 family member D

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MGAT4D, MGAT4 family member D
Synonyms

GnT1IP
Links

HGNC:43619

NCBI Gene ID: 152586

neXtProt AC: NX_A6NG13

UniProt: A6NG13
Chr Location

4q31.1; chr4:140442262-140498377 (-) GRCh38

MGI Vertebrate Homology

Mgat4d stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: MGAT4D
Gene Tree

Mgat4d

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Phenotype Summary

3 phenotypes from 2 alleles in 2 genetic backgrounds
40 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

9
Chemically induced (other)

1
Endonuclease-mediated

4
Radiation induced

1
Targeted

3
Genomic Mutations

2 involving Mgat4d
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

25 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Male mice exhibit normal testis size, testis to body weight, spermatozoa, and sperm motility.

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All GO Annotations

15
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

3

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase mgat4d

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All Sequences

32
RefSeq

4
UniProt

1
CCDS

CCDS22451.1

Ensembl

ENSMUSG00000035057 (Evidence)
NCBI Gene

67555

			Length	Strain/Species	Flank
genomic	67555	NCBI Gene Model \| MGI Sequence Detail	30931	C57BL/6J	± kb
transcript	NM_026233	RefSeq \| MGI Sequence Detail	1292	C57BL/6
polypeptide	Q9D4R2	UniProt \| EBI \| MGI Sequence Detail	373	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000059696 alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D

(term hierarchy)
InterPro Domains

IPR006759 Glycosyl transferase family 54

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All nucleic 3

cDNA 3

Microarray probesets 4

Summaries

All 60

Gene Ontology 4

Phenotypes 40
Earliest

J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54(1):113-145
Latest

J:286964 Akintayo A, et al., The Golgi Glycoprotein MGAT4D is an Intrinsic Protector of Testicular Germ Cells From Mild Heat Stress. Sci Rep. 2020 Feb 7;10(1):2135

TSS for Mgat4d:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr78260	Chr8:84075067-84075079 (+)	-28 bp
Tssr78261	Chr8:84075080-84075110 (+)	-6 bp
Tssr78262	Chr8:84075366-84075374 (+)	269 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23